Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5184388 | 0.88 | FAAH (0.47) | MEN1KMT2AMAPTHPGDFAAH | |
| SCHEMBL5186011 | 0.88 | ALDH1A1 (0.48) | MEN1KMT2APOLBGRM2GAA | |
| SCHEMBL17844161 | 0.86 | FAAH (0.44) | MEN1KMT2AGAAMAPTHPGD | |
| SCHEMBL17844132 | 0.85 | FAAH (0.39) | MEN1KMT2AHPGDFAAHMGLL | |
| SCHEMBL17844174 | 0.82 | FAAH (0.40) | MEN1KMT2AGAAMAPTHPGD | |
| SCHEMBL17844220 | 0.81 | FAAH (0.40) | MEN1KMT2AGAAHPGDFAAH | |
| SCHEMBL17844070 | 0.81 | FAAH (0.40) | MEN1KMT2AGAAHPGDFAAH | |
| SCHEMBL5185885 | 0.80 | LMNA (0.43) | MEN1KMT2APOLBGAAMAPT | |
| SCHEMBL5186704 | 0.80 | FAAH (0.38) | MEN1KMT2AGAAMAPTHPGD | |
| SCHEMBL17844060 | 0.79 | KDM4E (0.48) | KMT2APOLBGAAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |