Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5186011 | 0.90 | ALDH1A1 (0.48) | GAAMAPTSMN1; SMN2GRM2TP53 | |
| SCHEMBL17844142 | 0.88 | GAA (0.38) | GAAMAPTSMN1; SMN2GRM2TP53 | |
| SCHEMBL17844161 | 0.81 | FAAH (0.44) | GAAMAPTSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL5198203 | 0.81 | CASP3 (0.43) | GAAMAPTSMN1; SMN2ALDH1A1GLA | |
| SCHEMBL17844132 | 0.80 | FAAH (0.39) | ALDH1A1HSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL17844140 | 0.79 | SMN1; SMN2 (0.49) | GAAMAPTSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL17844070 | 0.79 | FAAH (0.40) | GAAALDH1A1GLAATML3MBTL1 | |
| SCHEMBL17844198 | 0.79 | MEN1 (0.48) | GAAMAPTSMN1; SMN2GRM2TP53 | |
| SCHEMBL5184388 | 0.78 | FAAH (0.47) | MAPTSMN1; SMN2TP53ALDH1A1ATM | |
| SCHEMBL5200606 | 0.78 | MEN1 (0.38) | GAAMAPTSMN1; SMN2TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |