Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844240 | 0.89 | CHRM4 (0.39) | JAK2JAK3GPR119SMO | |
| SCHEMBL17844219 | 0.88 | CKS1B (0.38) | GPR119SMO | |
| SCHEMBL5260026 | 0.87 | GPR119 (0.38) | GPR119SMO | |
| SCHEMBL17844162 | 0.87 | HRH3 (0.41) | MAPTKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL17844250 | 0.85 | KAT2B (0.41) | LMNAMAPTHTTKDM4EL3MBTL1 | |
| SCHEMBL5316660 | 0.84 | METAP1 (0.49) | LMNAMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3546550 | 0.81 | LMNA (0.42) | LMNAHTTSMN1; SMN2KDM4ETRPV1 | |
| SCHEMBL17844145 | 0.80 | HRH3 (0.38) | MAPTSMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL17844172 | 0.80 | GLS (0.43) | TRPV1 | |
| SCHEMBL17844164 | 0.78 | KAT2B (0.38) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |