Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844174 | 0.89 | FAAH (0.40) | FAAHMGLLALDH1A1MEN1KMT2A | |
| SCHEMBL17844161 | 0.86 | FAAH (0.44) | FAAHMGLLALDH1A1MEN1KMT2A | |
| SCHEMBL5186011 | 0.83 | ALDH1A1 (0.48) | FAAHMGLLALDH1A1MEN1KMT2A | |
| SCHEMBL5184388 | 0.83 | FAAH (0.47) | FAAHMGLLALDH1A1MEN1KMT2A | |
| SCHEMBL17844070 | 0.81 | FAAH (0.40) | FAAHMGLLALDH1A1MEN1KMT2A | |
| SCHEMBL17844198 | 0.81 | MEN1 (0.48) | FAAHMGLLALDH1A1MEN1KMT2A | |
| SCHEMBL17844132 | 0.80 | FAAH (0.39) | FAAHMGLLALDH1A1MEN1KMT2A | |
| SCHEMBL17844104 | 0.78 | HCRTR1 (0.38) | HPGD | |
| SCHEMBL5606522 | 0.77 | PLK1 (0.41) | FAAHMGLLALDH1A1MEN1KMT2A | |
| SCHEMBL17844158 | 0.77 | GAA (0.43) | ALDH1A1MEN1KMT2AL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |