SCHEMBL17844233

SCHEMBL17844233

O=C(OCC1CC2C=CC1C2)c1ccc(-c2ccc(OC(F)(F)F)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
MMP8 P22894 1/20 0.41
FFAR4 Q5NUL3 5/20 0.41
TP53 P04637 1/20 0.40
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
FASN P49327 1/20 0.39
CHRM2 P08172 1/20 0.38
CHRM1 P11229 1/20 0.38
AURKA O14965 1/20 0.38
TPX2 Q9ULW0 1/20 0.38
EPHX2 P34913 1/20 0.37
HSD11B1 P28845 1/20 0.36
PTGIR P43119 1/20 0.36
GPR119 Q8TDV5 1/20 0.36
HTR2B P41595 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19133368 0.96 TP53 (0.42) MMP2MMP9MMP8FFAR4TP53
SCHEMBL19133371 0.85 KDM4E (0.33) TP53HPGDSMN1; SMN2TDP1EPHX2
SCHEMBL417008 0.85 POLB (0.43) TDP1
SCHEMBL200865 0.84 KDM4E (0.47) SMN1; SMN2TDP1
SCHEMBL19133382 0.84 SMN1; SMN2 (0.40) FFAR4SMN1; SMN2TDP1
SCHEMBL4403504 0.79 PPM1B (0.47) TDP1
SCHEMBL14435505 0.79 PPM1B (0.47) TDP1
SCHEMBL19133376 0.76 TAS1R3 (0.39) FFAR4
SCHEMBL19133375 0.76 CES2 (0.38) SMN1; SMN2TDP1CHRM1HSD11B1
SCHEMBL17843616 0.76 KDM4E (0.42) FFAR4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3196236-B1 VERTICAL ALIGNMENT FILM COMPRISING (CO)POLYMER OF CYCLIC OLEFIN COMPOUND LG CHEMICAL LTD (KR) 2019-04-10 EP disclosed
US-10131843-B2 Vertical alignment layer comprising cyclic olefin copolymer LG CHEM, LTD. (KR) 2018-11-20 US disclosed
US-20170349834-A1 VERTICAL ALIGNMENT LAYER COMPRISING CYCLIC OLEFIN COPOLYMER LG CHEM, LTD. (KR) 2017-12-07 US disclosed
EP-3196236-A1 VERTICAL ALIGNMENT FILM COMPRISING (CO)POLYMER OF CYCLIC OLEFIN COMPOUND LG Chem, Ltd. (KR) 2017-07-26 EP disclosed
WO-2016099178-A1 VERTICAL ALIGNMENT FILM COMPRISING COPOLYMER OF CYCLIC OLEFIN COMPOUNDS 주식회사 엘지화학 2016-06-23 WO disclosed