SCHEMBL200865

SCHEMBL200865

O=C(OCC1CC2C=CC1C2)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.47
SLC1A5 Q15758 1/20 0.44
CHRNB2 P17787 1/20 0.43
CHRNB4 P30926 1/20 0.43
CHRNA3 P32297 1/20 0.43
CHRNA4 P43681 1/20 0.43
TDP1 Q9NUW8 3/20 0.43
ALDH1A1 P00352 2/20 0.43
NPY1R P25929 1/20 0.42
NPY2R P49146 1/20 0.42
PPM1B O75688 1/20 0.41
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40
KMT2A Q03164 1/20 0.40
LMNA P02545 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PKM P14618 1/20 0.40
CES2 O00748 1/20 0.40
DRD2 P14416 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14435505 0.92 PPM1B (0.47) KDM4ECHRNB2CHRNA4TDP1ALDH1A1
SCHEMBL4403504 0.92 PPM1B (0.47) KDM4ECHRNB2CHRNA4TDP1ALDH1A1
SCHEMBL417008 0.90 POLB (0.43) KDM4ETDP1ALDH1A1PPM1BKMT2A
SCHEMBL203002 0.89 FFAR4 (0.44) KDM4ETDP1ALDH1A1PPM1BSMN1; SMN2
SCHEMBL203802 0.87 KDM4E (0.45) KDM4ESLC1A5TDP1ALDH1A1NPY1R
SCHEMBL10023890 0.86 MAPT (0.46) KDM4ETDP1ALDH1A1PPM1BMEN1
SCHEMBL200326 0.85 TDP1 (0.46) KDM4ESLC1A5TDP1ALDH1A1NPY1R
SCHEMBL17844233 0.84 MMP2 (0.41) TDP1SMN1; SMN2
SCHEMBL201988 0.82 CHRNB2 (0.56) KDM4ECHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL200309 0.82 ALDH1A1 (0.46) KDM4ETDP1ALDH1A1MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3565850-B1 POLYCYCLOOLEFIN POLYMER COMPOSITIONS AS OPTICAL MATERIALS PROMERUS LLC (US) 2025-07-23 EP claimed
US-20250122402-A1 LONG SHELF-LIFE STABLE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS CONTAINING PYRIDINE LIGATED PALLADIUM COMPOUNDS PROMERUS, LLC (US) 2025-04-17 US claimed
US-11897991-B2 UV active derivatives of Pd(AcAc)2 catalyzed polycycloolefin compositions as optical materials PROMERUS, LLC (US) 2024-02-13 US claimed
US-11746166-B2 UV active derivatives of pd(AcAc)2L catalyzed polycycloolefin compositions as optical materials PROMERUS, LLC (US) 2023-09-05 US claimed
WO-2023158768-A1 DUAL CATALYST SYSTEM FOR MASS ROMP AND CATIONIC POLYMERIZABLE COMPOSITIONS PROMERUS, LLC (US) 2023-08-24 WO claimed
WO-2023158767-A1 DUAL CATALYST SYSTEM FOR MASS VINYL ADDITION AND CATIONIC POLYMERIZABLE COMPOSITIONS PROMERUS, LLC (US) 2023-08-24 WO claimed
US-11667731-B2 Stabilized UV active organopalladium compounds as vinyl addition catalysts PROMERUS, LLC (US) 2023-06-06 US claimed
US-20230038665-A1 STABILIZED UV ACTIVE ORGANOPALLADIUM COMPOUNDS AS VINYL ADDITON CATALYSTS PROMERUS, LLC (US) 2023-02-09 US claimed
WO-2023278649-A1 STABILIZED UV ACTIVE ORGANOPALLADIUM COMPOUNDS AS VINYL ADDITION CATALYSTS PROMERUS, LLC (US) 2023-01-05 WO claimed
US-20210198392-A1 UV ACTIVE DERIVATIVES OF Pd(AcAc)2 CATALYZED POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2021-07-01 US claimed
EP-3344671-B1 POLYCYCLOOLEFIN POLYMER COMPOSITIONS AS OPTICAL MATERIALS PROMERUS LLC (US) 2019-11-06 EP claimed
EP-3565850-B1 POLYCYCLOOLEFIN POLYMER COMPOSITIONS AS OPTICAL MATERIALS PROMERUS LLC (US) 2025-07-23 EP disclosed
US-20250122402-A1 LONG SHELF-LIFE STABLE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS CONTAINING PYRIDINE LIGATED PALLADIUM COMPOUNDS PROMERUS, LLC (US) 2025-04-17 US disclosed
US-11897991-B2 UV active derivatives of Pd(AcAc)2 catalyzed polycycloolefin compositions as optical materials PROMERUS, LLC (US) 2024-02-13 US disclosed
US-11760817-B2 Mass polymerizable polycycloolefin compositions containing soluble photoacid generators PROMERUS, LLC (US) 2023-09-19 US disclosed
EP-1626294-A2 Polarizing plate and process for producing the same JSR Corporation (JP) 2006-02-15 EP disclosed
US-20060027322-A1 Polarizing plate and process for producing the same JSR CORPORATION (JP) 2006-02-09 US disclosed
US-20040057141-A1 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2004-03-25 US disclosed
EP-1395855-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR Corporation (JP) 2004-03-10 EP disclosed
WO-2002088784-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR CORPORATION (JP) 2002-11-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11760817-B2 Mass polymerizable polycycloolefin compositions containing soluble photoacid generators PPOX, VCL, PFN1 KDM4E 3000/4885SLC1A5 2532/4885CHRNB2 3226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.