SCHEMBL417008

SCHEMBL417008

O=C(OCC1CC2C=CC1C2)c1ccc(C(=O)OCC2CC3C=CC2C3)cc1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.43
KMT2A Q03164 1/20 0.43
KDM4E B2RXH2 6/20 0.40
ALDH1A1 P00352 3/20 0.40
TDP1 Q9NUW8 3/20 0.40
RAB9A P51151 2/20 0.39
TSHR P16473 2/20 0.39
NPC1 O15118 1/20 0.39
PPM1B O75688 1/20 0.39
ALOX15 P16050 1/20 0.38
PKM P14618 1/20 0.37
CES2 O00748 1/20 0.37
DRD2 P14416 1/20 0.36
DRD4 P21917 1/20 0.36
HSP90AA1 P07900 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14435505 0.92 PPM1B (0.47) KMT2AKDM4EALDH1A1TDP1TSHR
SCHEMBL4403504 0.92 PPM1B (0.47) KMT2AKDM4EALDH1A1TDP1TSHR
SCHEMBL200865 0.90 KDM4E (0.47) KMT2AKDM4EALDH1A1TDP1PPM1B
SCHEMBL19133368 0.88 TP53 (0.42) POLBKMT2AKDM4ETDP1RAB9A
SCHEMBL10023890 0.87 MAPT (0.46) POLBKMT2AKDM4EALDH1A1TDP1
SCHEMBL19133375 0.86 CES2 (0.38) POLBKMT2AKDM4EALDH1A1TDP1
SCHEMBL200309 0.85 ALDH1A1 (0.46) POLBKMT2AKDM4EALDH1A1TDP1
SCHEMBL19133382 0.85 SMN1; SMN2 (0.40) POLBKMT2AKDM4EALDH1A1TDP1
SCHEMBL17844233 0.85 MMP2 (0.41) TDP1
SCHEMBL32688519 0.82 LMNA (0.48) KMT2AKDM4EALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4744462-A1 COMPOSITION Merck Patent GmbH (DE) 2026-05-20 EP disclosed
EP-4605438-A1 COMPOSITION Merck Patent GmbH (DE) 2025-08-27 EP disclosed
CN-120077076-A Composition and method for producing the same 默克专利有限公司 2025-05-30 CN disclosed
WO-2025012183-A1 COMPOSITION MERCK PATENT GMBH (DE) 2025-01-16 WO disclosed
EP-4437027-A1 DUAL UV BLOCKERS CONTAINING STABLE PHOTOACTIVE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS Promerus, LLC (US) 2024-10-02 EP disclosed
CN-118317992-A Dual UV blocker comprising a shelf-life stable photoactive bulk polymerized polycycloolefin composition as an optical material 普罗米鲁斯有限责任公司 2024-07-09 CN disclosed
WO-2024083874-A1 COMPOSITION MERCK PATENT GMBH (DE) 2024-04-25 WO disclosed
WO-2024083874-A1 COMPOSITION MERCK PATENT GMBH (DE) 2024-04-25 WO disclosed
EP-4288479-A1 LONG SHELF LIFE STABLE PHOTOACTIVE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS Promerus, LLC (US) 2023-12-13 EP disclosed
US-11795285-B2 Dual UV blockers containing stable photoactive mass polymerizable polycycloolefin compositions as optical materials PROMERUS, LLC (US) 2023-10-24 US disclosed
US-7820356-B2 photo-induced thermally developable film comprising norbornene-type polyalkenamer copolymer and a procatalyst; curable; transparent or colorless, and propagation loss SUMITOMO BAKELITE CO. LTD. (JP) 2010-10-26 US disclosed
US-7820356-B2 photo-induced thermally developable film comprising norbornene-type polyalkenamer copolymer and a procatalyst; curable; transparent or colorless, and propagation loss SUMITOMO BAKELITE CO. LTD. (JP) 2010-10-26 US disclosed
US-20100067861-A1 LIGHT GUIDE AND LIGHT GUIDE STRUCTURE SUMITOMO BAKELITE COMPANY LIMITED (JP) 2010-03-18 US disclosed
US-20100067861-A1 LIGHT GUIDE AND LIGHT GUIDE STRUCTURE SUMITOMO BAKELITE COMPANY LIMITED (JP) 2010-03-18 US disclosed
US-20100061688-A1 OPTICAL WAVEGUIDES AND METHODS THEREOF SUMITOMO BAKELITE CO., LTD. (JP) 2010-03-11 US disclosed
US-20100061688-A1 OPTICAL WAVEGUIDES AND METHODS THEREOF SUMITOMO BAKELITE CO., LTD. (JP) 2010-03-11 US disclosed
US-20100062378-A1 OPTICAL WAVEGUIDES AND METHODS THEREOF SUMITOMO BAKELITE CO., LTD. (JP) 2010-03-11 US disclosed
US-20100062378-A1 OPTICAL WAVEGUIDES AND METHODS THEREOF SUMITOMO BAKELITE CO., LTD. (JP) 2010-03-11 US disclosed
US-20070148566-A1 Optical waveguides and methods thereof SUMITOMO BAKELITE CO., LTD. (JP) 2007-06-28 US disclosed
US-20070148566-A1 Optical waveguides and methods thereof SUMITOMO BAKELITE CO., LTD. (JP) 2007-06-28 US disclosed