SCHEMBL17844664

SCHEMBL17844664

O=C(O)Oc1ccc(C2CC2)[nH]c1=O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.34
YTHDF2 Q9Y5A9 2/20 0.33
YTHDF3 Q7Z739 1/20 0.33
YTHDF1 Q9BYJ9 1/20 0.33
KDM5A P29375 1/20 0.33
KDM5B Q9UGL1 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GLA P06280 1/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
KDM4A O75164 1/20 0.30
KDM4C Q9H3R0 1/20 0.30
CCNT1 O60563 1/20 0.30
CDK9 P50750 1/20 0.30
CCNA2 P20248 1/20 0.30
CDK2 P24941 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17844617 0.80 PLAT (0.39)
SCHEMBL17844663 0.74 KDM4E (0.47) DAOYTHDF2YTHDF3YTHDF1KDM5A
SCHEMBL16794581 0.70 CCNA2 (0.35) DAOYTHDF2YTHDF3YTHDF1KDM5A
SCHEMBL3077346 0.68 HSD17B2 (0.40)
SCHEMBL17844662 0.68 KDM4E (0.57) KDM4EALDH1A1GAAHSD17B10
SCHEMBL3071416 0.68 HSD17B2 (0.34)
SCHEMBL30430358 0.67 HCAR2 (0.43) DAOYTHDF2YTHDF3YTHDF1KDM5A
SCHEMBL11833334 0.67 KDM5A (0.47) DAOKDM5AKDM5BHCAR2KDM4E
SCHEMBL3082984 0.66 HSD17B2 (0.32)
SCHEMBL9570985 0.65 PARP1 (0.38) DAOKDM4EPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016096942-A1 USE OF SELECTED PYRIDONE CARBOXAMIDES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-06-23 WO disclosed