SCHEMBL1784490

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1787465	0.97	KDR (0.39)	HSD11B1MAPK8ALDH1A1KDRRAB9A
	SCHEMBL1784269	0.82	KDR (0.42)	ALDH1A1KDRRAB9ANPC1HTT
	SCHEMBL1786820	0.81	KDR (0.46)	HSD11B1ALDH1A1KDRRAB9ANPC1
	SCHEMBL1786466	0.80	KDR (0.59)	HSD11B1ALDH1A1KDRRAB9ANPC1
	SCHEMBL1787441	0.79	KDR (0.42)	HSD11B1ALDH1A1KDRRAB9AHTT
	SCHEMBL1788101	0.78	NPC1 (0.40)	ALDH1A1KDRRAB9ANPC1HTT
	SCHEMBL1788104	0.78	KDR (0.47)	ALDH1A1KDRRAB9ANPC1KMT2A
	SCHEMBL1785787	0.77	DYRK1A (0.47)	KDR
	SCHEMBL1784703	0.77	DYRK1A (0.39)	ALDH1A1KDRNPC1KDM4EABL1
	SCHEMBL1786239	0.76	KDR (0.40)	HSD11B1MAPK8ALDH1A1KDRNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.