Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 4/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL359691 | 0.93 | METAP2 (0.47) | DHFRHDAC8NCF1CYP1A2HIF1A | |
| SCHEMBL15886634 | 0.86 | NCF1 (0.56) | DHFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12827741 | 0.81 | METAP2 (0.46) | HDAC8NCF1CYP1A2HIF1AMETAP2 | |
| SCHEMBL1507976 | 0.76 | DHFR (0.49) | DHFRALDH1A1KDM4E | |
| SCHEMBL25488411 | 0.74 | NCF1 (0.56) | NCF1CYP1A2LMNAALDH1A1MAPT | |
| SCHEMBL13371376 | 0.71 | NCF1 (0.62) | DHFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1507775 | 0.71 | PDE10A (0.46) | DHFRLMNAALDH1A1HPGDKMT2A | |
| SCHEMBL5943598 | 0.70 | NCF1 (0.52) | DHFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3230745 | 0.70 | METAP2 (0.58) | HDAC8NCF1CYP1A2HIF1AMETAP2 | |
| SCHEMBL8344571 | 0.70 | METAP2 (0.58) | HDAC8NCF1CYP1A2HIF1AMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012899-B2 | Electroluminescent metal complexes with nucleophilic carbene ligands | BASF SE (DE) | 2015-04-21 | — | — | US | disclosed |
| US-20130292660-A1 | ELECTROLUMINESCENT METAL COMPLEXES WITH NUCLEOPHILIC CARBENE LIGANDS | BASF SE (DE) | 2013-11-07 | — | — | US | disclosed |
| US-8492749-B2 | Electroluminescent metal complexes with nucleophilic carbene ligands | BASF SE (DE) | 2013-07-23 | — | — | US | disclosed |
| US-20110114922-A1 | Electroluminescent Metal Complexes with Nucleophilic Carbene Ligands | UDC IRELAND LIMITED (IE) | 2011-05-19 | — | — | US | disclosed |
| EP-2080796-A1 | Electroluminescent metal complexes with nucleophilic carbene ligands | Ciba Holding Inc. (CH) | 2009-07-22 | — | — | EP | disclosed |
| EP-1841834-A1 | ELECTROLUMINESCENT METAL COMPLEXES WITH NUCLEOPHILIC CARBENE LIGANDS | Ciba Specialty Chemicals Holding Inc. (CH) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006067074-A1 | ELECTROLUMINESCENT METAL COMPLEXES WITH NUCLEOPHILIC CARBENE LIGANDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110114922-A1 | Electroluminescent Metal Complexes with Nucleophilic Carbene Ligands | OCIAD1, OCIAD2, C1S | DHFR 4812/4885HDAC3 4511/4885HDAC4 4784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.