Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.58 |
| ▸ | PLAU | P00749 | 1/20 | 0.53 |
| ▸ | NCF1 | P14598 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | COMT | P21964 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8344571 | 0.89 | METAP2 (0.58) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| SCHEMBL4285012 | 0.78 | METAP2 (0.64) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| SCHEMBL12827741 | 0.77 | METAP2 (0.46) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| SCHEMBL12747684 | 0.76 | METAP2 (0.45) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| SCHEMBL359691 | 0.75 | METAP2 (0.47) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| 8-Hydroxy Quinaldine SCHEMBL29483489 | 0.74 | METAP2 (1.00) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| 8-Hydroxy Quinaldine SCHEMBL297247 | 0.74 | METAP2 (1.00) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| SCHEMBL18131613 | 0.73 | METAP2 (0.53) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| SCHEMBL5671692 | 0.73 | METAP2 (0.45) | METAP2PLAUNCF1ALOX12ALDH1A1 | |
| SCHEMBL21767732 | 0.73 | METAP2 (0.63) | METAP2PLAUNCF1ALOX12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | claimed |
| US-11701374-B1 | 8-hydroxy quinoline derivatives for enhancing telomerase reverse transcriptase (TERT) expression | SIERRA SCIENCES, INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-11701374-B1 | 8-hydroxy quinoline derivatives for enhancing telomerase reverse transcriptase (TERT) expression | SIERRA SCIENCES, INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-9302993-B2 | 8-hydroxy quinoline derivatives | PRANA BIOTECHNOLOGY LIMITED (AU) | 2016-04-05 | — | — | US | disclosed |
| US-9302993-B2 | 8-hydroxy quinoline derivatives | PRANA BIOTECHNOLOGY LIMITED (AU) | 2016-04-05 | — | — | US | disclosed |
| US-20150335635-A1 | 8-HYDROXY QUINOLINE DERIVATIVES | PRANA BIOTECHNOLOGY LIMITED (AU) | 2015-11-26 | — | — | US | disclosed |
| US-20150335635-A1 | 8-HYDROXY QUINOLINE DERIVATIVES | PRANA BIOTECHNOLOGY LIMITED (AU) | 2015-11-26 | — | — | US | disclosed |
| US-9169211-B2 | 8-hydroxy quinoline derivatives | PRANA BIOTECHNOLOGY LIMITED (AU) | 2015-10-27 | — | — | US | disclosed |
| US-9169211-B2 | 8-hydroxy quinoline derivatives | PRANA BIOTECHNOLOGY LIMITED (AU) | 2015-10-27 | — | — | US | disclosed |
| US-9163018-B2 | Method of treatment of age-related macular degeneration (AMD) | PRANA BIOTECHNOLOGY INC. (AU) | 2015-10-20 | — | — | US | disclosed |
| US-7132576-B2 | Method for isomerizing allyl alcohols | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-07 | — | — | US | disclosed |
| US-20050101807-A1 | Method for isomerizing allyl alcohols | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-12 | — | — | US | disclosed |
| US-6743526-B2 | STABLE ORGANOLUMINESCENT COMPOUNDS, E.G., A CHROMONE ALUMINUM OR ZINC CHELATE, BETWEEN A HOLE INJECTION ELECTRODE AND AN ELECTRON INJECTION ELECTRODE; CRYSTALLIZATION INHIBITION; DURABILITY; NO SHORT CIRCUITS; OXIDATION RESISTANCE | SANYO ELECTRIC CO., LTD. (JP) | 2004-06-01 | — | — | US | disclosed |
| US-20030170495-A1 | Organic electroluminescent device | SANYO ELECTRIC CO., LTD. (JP) | 2003-09-11 | — | — | US | disclosed |
| US-6555253-B2 | Emitting layer and carrier transport layer using organic material between hole injection electrode and electron injection electrode, wherein chelate compound of chromone derivative with zinc is used as organic material in one layer | SANYO ELECTRIC CO., LTD. (JP) | 2003-04-29 | — | — | US | disclosed |
| US-20020081453-A1 | Emitting layer and carrier transport layer using organic material between hole injection electrode and electron injection electrode, wherein chelate compound of chromone derivative with zinc is used as organic material in one layer | SANYO ELECTRIC CO., LTD. (JP) | 2002-06-27 | — | — | US | disclosed |
| US-6294273-B1 | EXHIBITS HOLE-INJECTING, HOLE-TRANSPORTING, ELECTROLUMINESCENT, ELECTRON-TRANSPORTING, AND ELECTRON-INJECTING FUNCTIONS, WHEREIN THE HOLE INJECTION ZONE CONTAINS AN UNCHARGED OR CATIONIC POLYTHIOPHENE | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-25 | — | — | US | disclosed |
| EP-1026924-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | Sanyo Electric Co., Ltd. (JP) | 2000-08-09 | — | — | EP | disclosed |
| WO-2000008128-A1 | FABRIC CARE COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2000-02-17 | — | — | WO | disclosed |
| EP-0964459-A2 | Electroluminescent devices containing N-alkyl-2,2'-imino-bis-(8-hydroxy-quinoline) metal complexes | Bayer Aktiengesellschaft (DE) | 1999-12-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150335635-A1 | 8-HYDROXY QUINOLINE DERIVATIVES | PARK7, COQ8A, NLN | METAP2 1832/4885PLAU 2218/4885NCF1 2693/4885 |
| US-11701374-B1 | 8-hydroxy quinoline derivatives for enhancing telomerase reverse transcriptase (TERT) expression | TERT, TERF2, RNGTT | METAP2 1330/4885PLAU 3003/4885NCF1 2599/4885 |
| US-20050101807-A1 | Method for isomerizing allyl alcohols | ADH1A, ADH1C, ADH5 | METAP2 680/4885PLAU 4336/4885NCF1 1247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.