Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845055 | 1.00 | TDP1 (0.44) | TDP1L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL27329821 | 0.77 | L3MBTL1 (0.42) | TDP1L3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL1681188 | 0.76 | HTT (0.67) | TDP1L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL19609971 | 0.74 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL4732560 | 0.74 | HTT (0.69) | TDP1L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL10659801 | 0.74 | ZDHHC20 (0.58) | TDP1L3MBTL1ALDH1A1HTTKDM4E | |
| SCHEMBL11753268 | 0.74 | EPHX1 (0.48) | HTT | |
| SCHEMBL11753262 | 0.74 | EPHX1 (0.48) | HTT | |
| SCHEMBL9179050 | 0.72 | EPHX1 (0.47) | — | |
| SCHEMBL12490812 | 0.72 | EPHX1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233978-B1 | COMPOSITIONS COMPRISING A POLYMERIC NETWORK | UNIV GENT (BE) | 2021-03-03 | — | — | EP | disclosed |
| EP-3233978-B1 | COMPOSITIONS COMPRISING A POLYMERIC NETWORK | UNIV GENT (BE) | 2021-03-03 | — | — | EP | disclosed |
| US-10246548-B2 | Compositions comprising a polymeric network | UNIVERSITEIT GENT (BE) | 2019-04-02 | — | — | US | disclosed |
| US-20170327625-A1 | COMPOSITIONS COMPRISING A POLYMERIC NETWORK | ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (FR) | 2017-11-16 | — | — | US | disclosed |
| EP-3233978-A1 | COMPOSITIONS COMPRISING A POLYMERIC NETWORK | Universiteit Gent (BE) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016097169-A1 | COMPOSITIONS COMPRISING A POLYMERIC NETWORK | UNIVERSITEIT GENT (BE) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016097169-A1 | COMPOSITIONS COMPRISING A POLYMERIC NETWORK | UNIVERSITEIT GENT (BE) | 2016-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170327625-A1 | COMPOSITIONS COMPRISING A POLYMERIC NETWORK | CHRNA5, CHRNA1, CHRM1 | TDP1 2945/4885L3MBTL1 3172/4885MEN1 1300/4885 |
| US-10246548-B2 | Compositions comprising a polymeric network | CHRNA5, CHRNA1, CHRM1 | TDP1 2763/4885L3MBTL1 3529/4885MEN1 1129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.