Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13212911 | 0.79 | ALDH1A1 (0.44) | ALDH1A1LTB4RLTB4R2MEN1KMT2A | |
| SCHEMBL22825659 | 0.76 | LMNA (0.42) | ALDH1A1LTB4RLTB4R2MEN1KMT2A | |
| SCHEMBL17845054 | 0.74 | TDP1 (0.44) | ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL17845055 | 0.74 | TDP1 (0.44) | ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL18603087 | 0.74 | LTB4R (0.40) | ALDH1A1LTB4RLTB4R2MEN1KMT2A | |
| SCHEMBL29842192 | 0.72 | LMNA (0.42) | ALDH1A1LTB4RLTB4R2POLBMEN1 | |
| SCHEMBL21004727 | 0.71 | ALDH1A1 (0.37) | ALDH1A1LTB4RLTB4R2MEN1KMT2A | |
| SCHEMBL6068855 | 0.69 | MAPT (0.48) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13078788 | 0.69 | POLB (0.75) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL761977 | 0.69 | POLB (0.75) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170327625-A1 | COMPOSITIONS COMPRISING A POLYMERIC NETWORK | ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (FR) | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170327625-A1 | COMPOSITIONS COMPRISING A POLYMERIC NETWORK | CHRNA5, CHRNA1, CHRM1 | ALDH1A1 2657/4885LTB4R 705/4885LTB4R2 552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.