SCHEMBL17845330

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31122003	1.00	ALDH1A1 (0.49)	ALDH1A1TDP1NPSR1TSHRSMN1; SMN2
	SCHEMBL28300945	0.83	ALDH1A1 (0.46)	ALDH1A1TDP1NPSR1TSHRSMN1; SMN2
	SCHEMBL2524312	0.82	TDP1 (0.58)	ALDH1A1TDP1TSHRSMN1; SMN2GPR35
	SCHEMBL2431059	0.81	TDP1 (0.64)	ALDH1A1TDP1NPSR1TSHRSMN1; SMN2
	SCHEMBL30800293	0.81	TDP1 (0.64)	ALDH1A1TDP1NPSR1TSHRSMN1; SMN2
	SCHEMBL16852115	0.78	ALDH1A1 (0.42)	ALDH1A1TDP1NPSR1SMN1; SMN2GPR35
	SCHEMBL4725240	0.77	TDP1 (0.48)	ALDH1A1TDP1TSHRSMN1; SMN2GPR35
	SCHEMBL3038035	0.77	RAB9A (0.48)	ALDH1A1TDP1NPSR1TSHRSMN1; SMN2
	SCHEMBL30627320	0.76	ALDH1A1 (0.50)	ALDH1A1TDP1NPSR1TSHRSMN1; SMN2
	SCHEMBL1999849	0.76	ALDH1A1 (0.50)	ALDH1A1TDP1NPSR1TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.