SCHEMBL17845348

SCHEMBL17845348

Cl[C]1OCCC1Nc1cccc(Cl)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FADS1 O60427 1/20 0.52
LMNA P02545 5/20 0.42
MEN1 O00255 5/20 0.40
KMT2A Q03164 5/20 0.40
NPC1 O15118 4/20 0.40
RAB9A P51151 4/20 0.40
TAAR1 Q96RJ0 1/20 0.39
MAOB P27338 1/20 0.39
HTT P42858 2/20 0.39
MAPT P10636 2/20 0.39
ALDH1A1 P00352 1/20 0.39
EPHX2 P34913 2/20 0.38
EPHX1 P07099 1/20 0.38
TSHR P16473 1/20 0.38
POLB P06746 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17845623 0.86 DDB1 (0.47) FADS1LMNAMEN1KMT2ATAAR1
SCHEMBL17845650 0.84 FADS1 (0.50) FADS1LMNAMEN1KMT2ANPC1
SCHEMBL17845716 0.84 FADS1 (0.50) FADS1LMNAMEN1KMT2ANPC1
SCHEMBL17845497 0.84 KDM4E (0.43) FADS1MEN1KMT2ANPC1RAB9A
SCHEMBL17845578 0.84 TSHR (0.39) FADS1MEN1KMT2ANPC1RAB9A
SCHEMBL17845380 0.83 DDB1 (0.40) FADS1HTTMAPTALDH1A1SMN1; SMN2
SCHEMBL4740571 0.82 FADS1 (0.62) FADS1LMNAMEN1KMT2ANPC1
SCHEMBL17845583 0.81 ROCK2 (0.46) LMNAMEN1KMT2ANPC1RAB9A
SCHEMBL17845534 0.80 POLB (0.42) LMNAMEN1KMT2ANPC1RAB9A
SCHEMBL4740830 0.77 FADS1 (0.49) FADS1LMNAMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3233860-A1 SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS Univerzita Palackého V Olomouci (CZ) 2017-10-25 EP disclosed
WO-2016095881-A1 SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2016-06-23 WO disclosed