Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845348 | 0.84 | FADS1 (0.52) | FADS1TAAR1LMNAMEN1KMT2A | |
| SCHEMBL17845575 | 0.82 | KDM4E (0.43) | TAAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL17845716 | 0.82 | FADS1 (0.50) | FADS1TAAR1LMNAMEN1KMT2A | |
| SCHEMBL17845573 | 0.82 | KMT2A (0.39) | MEN1KMT2ANPC1HTTDDB1 | |
| SCHEMBL17845490 | 0.79 | ROCK2 (0.49) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL4740571 | 0.79 | FADS1 (0.62) | FADS1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL17845623 | 0.77 | DDB1 (0.47) | FADS1TAAR1LMNAMEN1KMT2A | |
| SCHEMBL4740830 | 0.74 | FADS1 (0.49) | FADS1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL17845466 | 0.74 | ALDH1A1 (0.42) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL17845417 | 0.71 | DDB1 (0.43) | LMNANPC1RAB9AMAOBDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233860-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | Univerzita Palackého V Olomouci (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095881-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-23 | — | — | WO | disclosed |