Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845761 | 0.86 | DDB1 (0.43) | POLBALDH1A1RAB9AMAPTGAA | |
| SCHEMBL17845598 | 0.86 | ALDH1A1 (0.36) | POLBTRPA1ALDH1A1MEN1MAPT | |
| SCHEMBL17845595 | 0.86 | DDB1 (0.43) | POLBTRPA1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL17845380 | 0.85 | DDB1 (0.40) | TRPA1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10977584 | 0.82 | POLB (0.40) | POLBSMN1; SMN2ALDH1A1HDAC1HDAC8 | |
| SCHEMBL17845700 | 0.82 | GAA (0.46) | POLBSMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL17845348 | 0.80 | FADS1 (0.52) | POLBSMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL17845706 | 0.76 | RAB9A (0.40) | SMN1; SMN2ALDH1A1HDAC1HDAC8HDAC6 | |
| SCHEMBL17845623 | 0.75 | DDB1 (0.47) | ALDH1A1MEN1MAPTKMT2AGAA | |
| SCHEMBL17845497 | 0.74 | KDM4E (0.43) | TRPA1SMN1; SMN2RAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233860-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | Univerzita Palackého V Olomouci (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095881-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-23 | — | — | WO | disclosed |