Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845530 | 0.81 | GAA (0.41) | GAAKDM4EPOLBKMT2ANPC1 | |
| SCHEMBL17845555 | 0.78 | MAPT (0.43) | GAAKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL17845417 | 0.73 | DDB1 (0.43) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL17845575 | 0.72 | KDM4E (0.43) | GAAKDM4EKMT2ANPC1RAB9A | |
| SCHEMBL6426045 | 0.69 | GAA (0.60) | GAAKDM4EPOLBKMT2ANPC1 | |
| SCHEMBL29740616 | 0.69 | GAA (0.60) | GAAKDM4EPOLBKMT2ANPC1 | |
| SCHEMBL17845386 | 0.69 | ROCK2 (0.36) | GAAKDM4EROCK2 | |
| SCHEMBL17845784 | 0.68 | SMN1; SMN2 (0.40) | GAANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL17845502 | 0.68 | MAPT (0.47) | GAAKDM4EKMT2ARAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL1936838 | 0.67 | GAA (0.58) | GAAKDM4EPOLBKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233860-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | Univerzita Palackého V Olomouci (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095881-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-23 | — | — | WO | disclosed |