Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845530 | 0.88 | GAA (0.41) | P2RX7KDM4EGAA | |
| SCHEMBL17845762 | 0.86 | EPHX2 (0.36) | P2RX7 | |
| SCHEMBL17845453 | 0.78 | MEN1 (0.41) | P2RX7OPRL1 | |
| SCHEMBL17845726 | 0.78 | KMT2A (0.40) | P2RX7GAA | |
| SCHEMBL17845569 | 0.76 | GAA (0.38) | ROCK2P2RX7TP53GAA | |
| SCHEMBL17845720 | 0.75 | NPC1 (0.34) | P2RX7TP53GAA | |
| SCHEMBL17845502 | 0.75 | MAPT (0.47) | TP53KDM4EGAA | |
| SCHEMBL17845497 | 0.73 | KDM4E (0.43) | ROCK2KDM4EGAA | |
| SCHEMBL17845787 | 0.72 | MAPT (0.40) | KDM4EGAA | |
| SCHEMBL17845595 | 0.71 | DDB1 (0.43) | P2RX7DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233860-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | Univerzita Palackého V Olomouci (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095881-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-23 | — | — | WO | disclosed |