Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ICMT | O60725 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4318982 | 0.84 | KDM4E (0.43) | KDM4ETRPA1NPC1RAB9AMAOB | |
| SCHEMBL17845508 | 0.84 | CYP3A4 (0.39) | TRPA1NPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL17845716 | 0.84 | FADS1 (0.50) | NPC1RAB9AMAOBKMT2AMEN1 | |
| SCHEMBL17845575 | 0.84 | KDM4E (0.43) | KDM4ETRPA1NPC1RAB9AMAOB | |
| SCHEMBL17845497 | 0.84 | KDM4E (0.43) | KDM4ETRPA1NPC1RAB9AMAOB | |
| SCHEMBL17845542 | 0.83 | DDB1 (0.40) | TRPA1SMN1; SMN2 | |
| SCHEMBL17845615 | 0.81 | ROCK2 (0.46) | NPC1RAB9AKMT2AMEN1ROCK2 | |
| SCHEMBL17845532 | 0.78 | ROCK2 (0.42) | KDM4ENPC1RAB9AKMT2AMEN1 | |
| SCHEMBL1803049 | 0.73 | KDM4E (0.66) | KDM4ETRPA1NPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL1935990 | 0.72 | KDM4E (0.64) | KDM4ETRPA1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233860-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | Univerzita Palackého V Olomouci (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095881-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-23 | — | — | WO | disclosed |