Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845615 | 0.85 | ROCK2 (0.46) | ROCK2RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL17845449 | 0.85 | ROCK2 (0.42) | ROCK2SYKRAB9ANPC1HTT | |
| SCHEMBL17845602 | 0.78 | KDM4E (0.44) | ROCK2RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL17845716 | 0.75 | FADS1 (0.50) | RAB9ANPC1HTTSMN1; SMN2KMT2A | |
| SCHEMBL17845542 | 0.74 | DDB1 (0.40) | HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL17845550 | 0.72 | SYK (0.38) | ROCK2SYKRAB9ANPC1HTT | |
| SCHEMBL17845490 | 0.70 | ROCK2 (0.49) | ROCK2RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL17845768 | 0.70 | HTT (0.38) | ROCK2SYKRAB9ANPC1HTT | |
| SCHEMBL17845583 | 0.69 | ROCK2 (0.46) | ROCK2RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL18164614 | 0.69 | SMN1; SMN2 (0.44) | ROCK2SYKRAB9ANPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233860-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | Univerzita Palackého V Olomouci (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095881-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-23 | — | — | WO | disclosed |