Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 3/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845710 | 0.83 | EPHX2 (0.38) | GAAKDM4EKDM1AEPHX2POLB | |
| SCHEMBL17845563 | 0.82 | ALDH1A1 (0.34) | GAAKDM1ANPC1RAB9AALDH1A1 | |
| SCHEMBL17845614 | 0.82 | GAA (0.40) | GAAKDM4EEPHX2POLBKMT2A | |
| SCHEMBL17845714 | 0.78 | SMN1; SMN2 (0.38) | GAANPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL17845669 | 0.78 | ALDH1A1 (0.40) | GAAKDM1AALDH1A1SMN1; SMN2KDM1B | |
| SCHEMBL17845473 | 0.71 | TP53 (0.33) | GAAKDM4E | |
| SCHEMBL17845590 | 0.69 | SMN1; SMN2 (0.40) | GAAPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL17845643 | 0.68 | KMT2A (0.37) | KDM1AEPHX2KMT2ANPC1ALDH1A1 | |
| SCHEMBL6426045 | 0.67 | GAA (0.60) | GAAKDM4EKDM1APOLBKMT2A | |
| SCHEMBL29740616 | 0.67 | GAA (0.60) | GAAKDM4EKDM1APOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233860-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | Univerzita Palackého V Olomouci (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095881-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-23 | — | — | WO | disclosed |