Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845659 | 0.83 | TSHR (0.37) | KMT2ACYP3A4TSHRNPC1ALDH1A1 | |
| SCHEMBL17845655 | 0.83 | TSHR (0.37) | KMT2ACYP3A4TSHRNPC1ALDH1A1 | |
| SCHEMBL17845626 | 0.83 | FADS1 (0.42) | KMT2ACYP3A4TSHRNPC1ALDH1A1 | |
| SCHEMBL17845763 | 0.83 | KDM4E (0.41) | KMT2ANPC1MEN1KDM1AMAOB | |
| SCHEMBL17845711 | 0.82 | ALDH1A1 (0.35) | KMT2AALDH1A1MEN1KDM1A | |
| SCHEMBL17845669 | 0.82 | ALDH1A1 (0.40) | CYP3A4ALDH1A1CYP1A2LMNARECQL | |
| SCHEMBL17845540 | 0.80 | RAB9A (0.43) | KMT2ANPC1ALDH1A1MEN1LMNA | |
| SCHEMBL17845751 | 0.75 | ALDH1A1 (0.47) | KMT2ANPC1ALDH1A1MEN1LMNA | |
| SCHEMBL17845563 | 0.74 | ALDH1A1 (0.34) | TSHRNPC1ALDH1A1LMNAALOX15 | |
| SCHEMBL17845590 | 0.73 | SMN1; SMN2 (0.40) | NPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233860-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | Univerzita Palackého V Olomouci (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095881-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-23 | — | — | WO | disclosed |