SCHEMBL17845669

SCHEMBL17845669

NC1[CH]OCCC1Nc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
LMNA P02545 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
GAA P10253 1/20 0.33
KDM1A O60341 5/20 0.32
MAOB P27338 3/20 0.32
MAOA P21397 2/20 0.32
DDB1 Q16531 1/20 0.32
CRBN Q96SW2 1/20 0.32
KDM1B Q8NB78 1/20 0.32
RCOR1 Q9UKL0 1/20 0.32
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
KCNH3 Q9ULD8 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17845590 0.83 SMN1; SMN2 (0.40) ALDH1A1LMNASMN1; SMN2GAA
SCHEMBL17845711 0.83 ALDH1A1 (0.35) ALDH1A1GAAKDM1A
SCHEMBL17845643 0.82 KMT2A (0.37) ALDH1A1LMNAKDM1AMAOBMAOA
SCHEMBL17845626 0.82 FADS1 (0.42) ALDH1A1LMNAGAACYP1A2CYP3A4
SCHEMBL17845717 0.80 MAPK1 (0.39) ALDH1A1SMN1; SMN2GAAKDM1AMAOB
SCHEMBL17845760 0.79 ALDH1A1 (0.40) ALDH1A1LMNASMN1; SMN2GAADDB1
SCHEMBL17845600 0.79 ALDH1A1 (0.40) ALDH1A1LMNASMN1; SMN2GAADDB1
SCHEMBL17845540 0.78 RAB9A (0.43) ALDH1A1LMNASMN1; SMN2
SCHEMBL17845563 0.78 ALDH1A1 (0.34) ALDH1A1LMNASMN1; SMN2GAAKDM1A
SCHEMBL17845666 0.78 GAA (0.37) ALDH1A1SMN1; SMN2GAAKDM1ADDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3233860-A1 SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS Univerzita Palackého V Olomouci (CZ) 2017-10-25 EP disclosed
WO-2016095881-A1 SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2016-06-23 WO disclosed