Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.31 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845492 | 0.85 | ALDH1A1 (0.35) | EPHX1 | |
| SCHEMBL17845764 | 0.85 | SMN1; SMN2 (0.40) | POLBRAB9ANPC1TRPA1EPHX1 | |
| SCHEMBL17845600 | 0.85 | ALDH1A1 (0.40) | DDB1CRBNTRPA1LMNASMN1; SMN2 | |
| SCHEMBL17845696 | 0.82 | DDB1 (0.35) | DDB1CRBNPOLBRAB9ANPC1 | |
| SCHEMBL17845579 | 0.82 | DDB1 (0.35) | DDB1CRBNPOLBRAB9ANPC1 | |
| SCHEMBL17845587 | 0.81 | GAA (0.39) | POLBRAB9ANPC1EPHX1CAPN1 | |
| SCHEMBL17845628 | 0.81 | KDM4E (0.42) | POLBRAB9ANPC1TRPA1SMN1; SMN2 | |
| SCHEMBL17845659 | 0.74 | TSHR (0.37) | RAB9ANPC1LMNA | |
| SCHEMBL17845512 | 0.74 | FADS1 (0.42) | POLBRAB9ANPC1EPHX1LMNA | |
| SCHEMBL17845581 | 0.74 | RAB9A (0.43) | POLBRAB9ANPC1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233860-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | Univerzita Palackého V Olomouci (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095881-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-23 | — | — | WO | disclosed |