Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845778 | 0.85 | DDB1 (0.36) | SMN1; SMN2LMNATRPA1DDB1CRBN | |
| SCHEMBL17845492 | 0.83 | ALDH1A1 (0.35) | ALDH1A1GAA | |
| SCHEMBL17845628 | 0.83 | KDM4E (0.42) | ALDH1A1SMN1; SMN2GAATRPA1 | |
| SCHEMBL17845512 | 0.82 | FADS1 (0.42) | ALDH1A1LMNA | |
| SCHEMBL17845659 | 0.82 | TSHR (0.37) | ALDH1A1LMNARECQL | |
| SCHEMBL17845587 | 0.80 | GAA (0.39) | ALDH1A1SMN1; SMN2GAARECQL | |
| SCHEMBL17845669 | 0.79 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2LMNAGAADDB1 | |
| SCHEMBL17845760 | 0.79 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2LMNAGAADDB1 | |
| SCHEMBL17845581 | 0.78 | RAB9A (0.43) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL17845582 | 0.78 | KMT2A (0.42) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233860-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | Univerzita Palackého V Olomouci (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095881-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-23 | — | — | WO | disclosed |