SCHEMBL17847282

SCHEMBL17847282

COc1ccccc1C1CC(C)CCC1C(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 3/20 0.46
HTR2A P28223 1/20 0.46
HTR2B P41595 1/20 0.46
KCNA5 P22460 1/20 0.43
ALDH1A1 P00352 3/20 0.42
LMNA P02545 1/20 0.42
TRPV1 Q8NER1 2/20 0.40
HPGD P15428 2/20 0.40
TRPM8 Q7Z2W7 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
KDM4E B2RXH2 1/20 0.39
GLA P06280 1/20 0.39
GAA P10253 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MEN1 O00255 1/20 0.38
USP2 O75604 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30506638 1.00 HTR2C (0.46) HTR2CHTR2AHTR2BKCNA5ALDH1A1
SCHEMBL10700915 0.86 KCNA5 (0.50) KCNA5ALDH1A1LMNATRPV1HPGD
SCHEMBL25005231 0.84 HTR2C (0.53) HTR2CHTR2AHTR2BALDH1A1CA1
SCHEMBL21169205 0.84 HTR2C (0.53) HTR2CHTR2AHTR2BALDH1A1CA1
SCHEMBL8202662 0.80 KDM1A (0.45) KCNA5ALDH1A1LMNATRPV1HPGD
SCHEMBL8498802 0.80 KCNA5 (0.46) HTR2CHTR2AHTR2BKCNA5ALDH1A1
SCHEMBL8336802 0.79 KCNA5 (0.44) KCNA5ALDH1A1LMNATRPV1HPGD
SCHEMBL5824341 0.79 OPRM1 (0.47) HTR2CHTR2AHTR2BKCNA5ALDH1A1
SCHEMBL8595586 0.79 ALDH1A1 (0.41) KCNA5ALDH1A1LMNATRPV1HPGD
SCHEMBL11051375 0.78 TRPV1 (0.35) KCNA5ALDH1A1LMNATRPV1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116898893-A Compound birch oil mint cream and preparation and use methods thereof 山东乐智医疗科技有限公司 2023-10-20 CN disclosed
US-11246810-B2 Sprayable cosmetic agent II HENKEL AG & CO. KGAA (DE) 2022-02-15 US disclosed
EP-3233046-B1 USE OF A COMBINATION OF AN ASSOCIATIVE NONIONIC POLYETHER POLYURETHANE AND A CYCLOHEXANOL DERIVATIVE AS A SKIN REFRESHING AGENT OREAL (FR) 2020-07-29 EP disclosed
EP-3600230-A1 SPRAYABLE COSMETIC AGENT II Henkel AG & Co. KGaA (DE) 2020-02-05 EP disclosed
US-10548833-B2 Use of a combination of an associative nonionic polyether polyurethane and a cyclohexanol derivative as a skin refreshing agent L'OREAL (FR) 2020-02-04 US disclosed
US-20200030196-A1 SPRAYABLE COSMETIC AGENT II HENKEL AG & CO. KGAA (DE) 2020-01-30 US disclosed
WO-2018177721-A1 SPRAYABLE COSMETIC AGENT II HENKEL AG & CO. KGAA (DE) 2018-10-04 WO disclosed
US-20170367965-A1 USE OF A COMBINATION OF AN ASSOCIATIVE NONIONIC POLYETHER POLYURETHANE AND A CYCLOHEXANOL DERIVATIVE AS A SKIN REFRESHING AGENT L'OREAL (FR) 2017-12-28 US disclosed
EP-3233046-A1 USE OF A COMBINATION OF AN ASSOCIATIVE NONIONIC POLYETHER POLYURETHANE AND A CYCLOHEXANOL DERIVATIVE AS A SKIN REFRESHING AGENT L'Oréal (FR) 2017-10-25 EP disclosed
WO-2016096928-A1 USE OF A COMBINATION OF AN ASSOCIATIVE NONIONIC POLYETHER POLYURETHANE AND A CYCLOHEXANOL DERIVATIVE AS A SKIN REFRESHING AGENT L'OREAL (FR) 2016-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10548833-B2 Use of a combination of an associative nonionic polyether polyurethane and a cyclohexanol derivative as a skin refreshing agent CUTA, DEGS1, OR51E2 HTR2C 622/4885HTR2A 932/4885HTR2B 970/4885
US-20170367965-A1 USE OF A COMBINATION OF AN ASSOCIATIVE NONIONIC POLYETHER POLYURETHANE AND A CYCLOHEXANOL DERIVATIVE AS A SKIN REFRESHING AGENT CUTA, DEGS1, OR51E2 HTR2C 622/4885HTR2A 932/4885HTR2B 970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.