Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HMGCR | P04035 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1785809 | 0.91 | ALDH1A1 (0.38) | ALDH1A1CYP3A4HMGCRGAAIDH1 | |
| SCHEMBL931514 | 0.83 | ALDH1A1 (0.51) | ALDH1A1CYP3A4HMGCRGAATDP1 | |
| SCHEMBL1783070 | 0.80 | HMGCR (0.38) | ALDH1A1CYP3A4HMGCRGAATDP1 | |
| Phosphoric Acid SCHEMBL15754223 | 0.78 | HMGCR (0.47) | ALDH1A1CYP3A4HMGCRGAATDP1 | |
| SCHEMBL14000556 | 0.78 | HMGCR (0.41) | ALDH1A1CYP3A4HMGCRGAATDP1 | |
| SCHEMBL11649063 | 0.77 | THRB (0.42) | HMGCRGAATDP1TSHRHTT | |
| SCHEMBL9511287 | 0.76 | ALDH1A1 (0.41) | ALDH1A1CYP3A4HMGCRGAATDP1 | |
| SCHEMBL1785393 | 0.74 | ALDH1A1 (0.43) | ALDH1A1CYP3A4HMGCRGAATDP1 | |
| SCHEMBL28850429 | 0.74 | HMGCR (0.49) | ALDH1A1CYP3A4HMGCRGAATDP1 | |
| SCHEMBL14010965 | 0.74 | HSPA5 (0.59) | ALDH1A1CYP3A4HMGCRGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796939-B2 | Multi-ring antioxidants with antiwear properties | SI GROUP, INC. (US) | 2017-10-24 | — | — | US | disclosed |
| US-20140038871-A1 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | ALBEMARLE CORPORATION (US) | 2014-02-06 | — | — | US | disclosed |
| US-8580718-B2 | Multi-ring antioxidants with antiwear properties | ALBERMARLE CORPORATION (US) | 2013-11-12 | — | — | US | disclosed |
| US-20110124540-A1 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | ALBEMARLE CORPORATION (US) | 2011-05-26 | — | — | US | disclosed |
| EP-2323975-A2 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | Albemarle Corporation (US) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010011523-A2 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | ALBEMARLE CORPORATION (US) | 2010-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124540-A1 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | GSR, CBR1, SOD1 | ALDH1A1 118/4885CYP3A4 811/4885HMGCR 145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.