Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.33 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1784735 | 0.91 | ALDH1A1 (0.42) | ALDH1A1CYP3A4IDH1CYP1A2CYP2C9 | |
| SCHEMBL1786090 | 0.82 | CYP1A2 (0.36) | ALDH1A1CYP1A2CYP2C9CYP2C19HMGCR | |
| SCHEMBL1785658 | 0.81 | ALDH1A1 (0.38) | ALDH1A1CYP3A4S1PR4IDH1HMGB1 | |
| SCHEMBL13057612 | 0.80 | ALDH1A1 (0.52) | ALDH1A1CYP3A4S1PR4IDH1HMGB1 | |
| SCHEMBL9514191 | 0.79 | SHBG (0.46) | ALDH1A1CYP3A4HMGB1CXCL12CYP1A2 | |
| SCHEMBL1783230 | 0.77 | SHBG (0.41) | ALDH1A1CYP3A4HMGB1CXCL12CYP1A2 | |
| SCHEMBL931514 | 0.76 | ALDH1A1 (0.51) | ALDH1A1CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11783326 | 0.73 | CYP2C9 (0.44) | ALDH1A1CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14000556 | 0.73 | HMGCR (0.41) | ALDH1A1CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5083340 | 0.72 | CYP1A2 (0.46) | ALDH1A1CYP3A4CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796939-B2 | Multi-ring antioxidants with antiwear properties | SI GROUP, INC. (US) | 2017-10-24 | — | — | US | disclosed |
| US-20140038871-A1 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | ALBEMARLE CORPORATION (US) | 2014-02-06 | — | — | US | disclosed |
| US-8580718-B2 | Multi-ring antioxidants with antiwear properties | ALBERMARLE CORPORATION (US) | 2013-11-12 | — | — | US | disclosed |
| US-20110124540-A1 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | ALBEMARLE CORPORATION (US) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124540-A1 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | GSR, CBR1, SOD1 | ALDH1A1 118/4885CYP3A4 811/4885S1PR4 1795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.