SCHEMBL17847375

SCHEMBL17847375

CC(C)(C)CC(C)(C)C(Oc1ccccc1)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.43
PPARA Q07869 9/20 0.41
PPARG P37231 8/20 0.41
MTNR1A P48039 3/20 0.41
MTNR1B P49286 3/20 0.41
CYP1A2 P05177 1/20 0.40
GAA P10253 1/20 0.40
CYP2C9 P11712 1/20 0.40
PKM P14618 1/20 0.40
CYP2C19 P33261 1/20 0.40
EDNRB P24530 2/20 0.39
EDNRA P25101 2/20 0.39
POLB P06746 1/20 0.39
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL28597924 0.97 ALOX15 (0.41) ALOX15PPARAPPARGMTNR1AMTNR1B
SCHEMBL28599039 0.86 PPARA (0.38) ALOX15PPARAPPARGMTNR1AMTNR1B
SCHEMBL2046224 0.85 ALOX15 (0.44) ALOX15PPARAPPARGMTNR1AMTNR1B
SCHEMBL7037791 0.80 ATM (0.47) PPARAPPARGMTNR1AMTNR1BCYP1A2
SCHEMBL5503297 0.76 EDNRB (0.44) ALOX15PPARAPPARGMTNR1AMTNR1B
SCHEMBL6699933 0.75 PPARG (0.40) PPARAPPARGMTNR1AMTNR1BCYP1A2
SCHEMBL7322928 0.74 ATM (0.49) PPARAPPARGMTNR1AMTNR1BCYP1A2
SCHEMBL22260771 0.73 MTNR1A (0.34) PPARAPPARGMTNR1AMTNR1BCYP1A2
SCHEMBL1577777 0.73 CYP1A2 (0.46) PPARAPPARGMTNR1AMTNR1BCYP1A2
SCHEMBL8132529 0.72 PPARA (0.40) ALOX15PPARAPPARGMTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023168066-A9 OXIME-BASED HOT MELT ADHESIVES FOR REWORK, REPAIR AND RECYCLE CONAGEN INC. (US) 2024-06-20 WO disclosed
EP-4337639-A1 NAMPT INHIBITORS AND USES THEREOF Remedy Plan, Inc. (US) 2024-03-20 EP disclosed
WO-2023201005-A2 HYDROPHOBIC POLYMER AEROGELS AEROGEL TECHNOLOGIES, LLC (US) 2023-10-19 WO disclosed
WO-2023168066-A1 OXIME-BASED HOT MELT ADHESIVES FOR REWORK, REPAIR AND RECYCLE CONAGEN INC. (US) 2023-09-07 WO disclosed
WO-2023168045-A1 HYDROXY/AMINO OXIME-BASED HOT MELT ADHESIVES FOR REWORK, REPAIR AND RECYCLE CONAGEN INC. (US) 2023-09-07 WO disclosed
US-20230158159-A1 CHIMERIC DEGRADERS OF CYCLIN-DEPENDENT KINASE 9 AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-05-25 US disclosed
CN-114604951-B Application of p-tert-octyl phenoxy carboxylic acid in copper-containing wastewater treatment 厦门稀土材料研究所 2023-05-09 CN disclosed
CN-113201649-B Phenoxy carboxylic acid solid-phase extracting agent, and preparation method and application thereof 福建省长汀金龙稀土有限公司 2023-04-11 CN disclosed
WO-2022241257-A1 NAMPT INHBITORS AND USES THEREOF REMEDY PLAN, INC. (US) 2022-11-17 WO disclosed
CN-114604951-A Application of p-tert-octyl phenoxy carboxylic acid in copper-containing wastewater treatment 厦门稀土材料研究所 2022-06-10 CN disclosed
WO-2018067973-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2018-04-12 WO disclosed
WO-2017192664-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2017-11-09 WO disclosed
WO-2017192679-A1 METHODS AND COMPOSITIONS OF BIOLOGICALLY ACTIVE AGENTS WAVE LIFE SCIENCES LTD. (SG) 2017-11-09 WO disclosed
EP-3234175-A1 ENZYMATIC ACTIVITY ASSAYS FOR I2S Shire Human Genetic Therapies, Inc. (US) 2017-10-25 EP disclosed
WO-2017062862-A2 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2017-04-13 WO disclosed
WO-2017062622-A1 SUPRAMOLECULAR MODIFICATION OF PROTEINS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-04-13 WO disclosed
WO-2017015555-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2017-01-26 WO disclosed
WO-2017015575-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2017-01-26 WO disclosed
WO-2016100603-A9 ENZYMATIC ACTIVITY ASSAYS FOR I2S SHIRE HUMAN GENETIC THERAPIES, INC. (US) 2016-08-11 WO disclosed
WO-2016100603-A1 ENZYMATIC ACTIVITY ASSAYS FOR I2S SHIRE HUMAN GENETIC THERAPIES, INC. (US) 2016-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158159-A1 CHIMERIC DEGRADERS OF CYCLIN-DEPENDENT KINASE 9 AND USES THEREOF CDK9, CDK19, CRBN ALOX15 4637/4885PPARA 3922/4885PPARG 3304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.