SCHEMBL17847446

SCHEMBL17847446

CCc1c(OC#N)cccc1-c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 3/20 0.39
HTR7 P34969 2/20 0.37
CYP2C9 P11712 1/20 0.37
S1PR1 P21453 1/20 0.37
MAPK1 P28482 2/20 0.36
TP53 P04637 1/20 0.36
RAB9A P51151 1/20 0.36
CD274 Q9NZQ7 2/20 0.35
KDM4E B2RXH2 3/20 0.35
L3MBTL1 Q9Y468 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.35
GRIA2 P42262 2/20 0.34
GRIA4 P48058 2/20 0.34
PDCD1 Q15116 1/20 0.34
ADRB1 P08588 1/20 0.34
ALDH1A1 P00352 2/20 0.33
ADORA2A P29274 2/20 0.33
ADORA1 P30542 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2159608 0.79 MAPK1 (0.44) ADRB2HTR7MAPK1TP53RAB9A
Hydrogen Sulfide SCHEMBL27519355 0.77 MAPK1 (0.43) ADRB2HTR7MAPK1TP53RAB9A
SCHEMBL9806251 0.76 PDCD1 (0.47) ADRB2HTR7MAPK1TP53CD274
SCHEMBL583708 0.76 TDP1 (0.37) ADRB2HTR7MAPK1TP53RAB9A
SCHEMBL8763456 0.75 GABRA1 (0.36) CYP2C9S1PR1L3MBTL1
SCHEMBL6278704 0.75 ESR2 (0.44) CYP2C9S1PR1MAPK1CD274KDM4E
SCHEMBL7941977 0.74 L3MBTL1 (0.43) MAPK1RAB9AKDM4EL3MBTL1TDP1
SCHEMBL27956482 0.73 CD274 (0.47) CYP2C9S1PR1MAPK1CD274KDM4E
SCHEMBL5197652 0.73 ADORA3 (0.50) CYP2C9MAPK1KDM4EL3MBTL1TDP1
Water SCHEMBL27696696 0.72 PDCD1 (0.48) CYP2C9S1PR1CD274PDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3233791-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA Covestro Deutschland AG (DE) 2017-10-25 EP disclosed
WO-2016096641-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA COVESTRO DEUTSCHLAND AG (DE) 2016-06-23 WO disclosed