SCHEMBL17847473

SCHEMBL17847473

CCCCCCc1ccc(N=C=O)c(-c2ccccc2)c1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ PSMB5 P28074 1/20 0.45
▸ GPR3 P46089 1/20 0.43
▸ RARB P10826 6/20 0.41
▸ KAT8 Q9H7Z6 2/20 0.41
▸ HSD11B1 P28845 1/20 0.41
▸ PPARA Q07869 1/20 0.41
▸ LPL P06858 1/20 0.40
▸ LIPG Q9Y5X9 1/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ RARA P10276 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ MTOR P42345 1/20 0.40
▸ KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17847499 1.00 PSMB5 (0.45) PSMB5GPR3RARBKAT8HSD11B1
SCHEMBL28173859 0.99 PSMB5 (0.46) PSMB5GPR3RARBKAT8HSD11B1
SCHEMBL17847497 0.95 PSMB5 (0.50) PSMB5GPR3RARBHSD11B1ALDH1A1
SCHEMBL19713048 0.89 CNR2 (0.40) PSMB5ALDH1A1
SCHEMBL17847511 0.83 ALDH1A1 (0.44) PSMB5ALDH1A1MAPT
SCHEMBL28472275 0.81 BACE1 (0.38) PSMB5ALDH1A1
SCHEMBL11385174 0.81 PSMB5 (0.49) PSMB5GPR3RARBKAT8HSD11B1
SCHEMBL22318919 0.80 MMP12 (0.40) PSMB5ALDH1A1
SCHEMBL28899630 0.78 PPARA (0.55) KAT8PPARAALDH1A1
SCHEMBL17847496 0.77 FOLH1 (0.49) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107223121-B Wet stable holographic media 科思创德国股份有限公司 2020-10-27 — — CN disclosed
EP-3233791-B1 MOISTURE STABLE HOLOGRAPHIC MEDIA COVESTRO DEUTSCHLAND AG (DE) 2020-08-12 — — EP disclosed
US-10329244-B2 Moisture-stable holographic media COVESTRO DEUTSCHLAND AG (DE) 2019-06-25 — — US disclosed
US-20170362165-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA COVESTRO DEUTSCHLAND AG (DE) 2017-12-21 — — US disclosed
EP-3233791-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA Covestro Deutschland AG (DE) 2017-10-25 — — EP disclosed
CN-107223121-A Wet stable holographic media 科思创德国股份有限公司 2017-09-29 — — CN disclosed
WO-2016096641-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA COVESTRO DEUTSCHLAND AG (DE) 2016-06-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10329244-B2 Moisture-stable holographic media NEFM, MDM4, BHMT2 PSMB5 2023/4885GPR3 4747/4885RARB 4325/4885
US-20170362165-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA NEFM, MDM4, BHMT2 PSMB5 2023/4885GPR3 4747/4885RARB 4325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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