SCHEMBL17847497

SCHEMBL17847497

CCCCc1ccc(N=C=O)c(-c2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PSMB5 P28074 1/20 0.50
▸ HSD11B1 P28845 2/20 0.40
▸ METAP2 P50579 1/20 0.38
▸ CYP1A2 P05177 1/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ CYP2D6 P10635 1/20 0.37
▸ CYP2C9 P11712 1/20 0.37
▸ CYP2C19 P33261 1/20 0.37
▸ CYP4Z1 Q86W10 1/20 0.37
▸ CYP4F11 Q9HBI6 1/20 0.37
▸ CYP4F12 Q9HCS2 1/20 0.37
▸ RARB P10826 2/20 0.37
▸ BRS3 P32247 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.36
▸ HPGD P15428 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.36
▸ BACE1 P56817 1/20 0.36
▸ TRPV1 Q8NER1 1/20 0.36
▸ GPR3 P46089 1/20 0.36
▸ LTB4R2 Q9NPC1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28173859 0.96 PSMB5 (0.46) PSMB5HSD11B1RARBALDH1A1GPR3
SCHEMBL17847473 0.95 PSMB5 (0.45) PSMB5HSD11B1RARBALDH1A1GPR3
SCHEMBL17847499 0.95 PSMB5 (0.45) PSMB5HSD11B1RARBALDH1A1GPR3
SCHEMBL19713048 0.92 CNR2 (0.40) PSMB5METAP2CYP3A4ALDH1A1HPGD
SCHEMBL17847511 0.85 ALDH1A1 (0.44) PSMB5METAP2CYP1A2CYP3A4ALDH1A1
SCHEMBL28472275 0.83 BACE1 (0.38) PSMB5CYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL22318919 0.82 MMP12 (0.40) PSMB5CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL28481092 0.82 GPR3 (0.36) PSMB5METAP2CYP1A2CYP3A4CYP2D6
SCHEMBL28279410 0.81 PSMB5 (0.53) PSMB5HSD11B1METAP2RARBBRS3
SCHEMBL17847496 0.80 FOLH1 (0.49) CYP3A4ALDH1A1HPGDBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107223121-B Wet stable holographic media 科思创德国股份有限公司 2020-10-27 — — CN disclosed
EP-3233791-B1 MOISTURE STABLE HOLOGRAPHIC MEDIA COVESTRO DEUTSCHLAND AG (DE) 2020-08-12 — — EP disclosed
US-10329244-B2 Moisture-stable holographic media COVESTRO DEUTSCHLAND AG (DE) 2019-06-25 — — US disclosed
US-20170362165-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA COVESTRO DEUTSCHLAND AG (DE) 2017-12-21 — — US disclosed
EP-3233791-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA Covestro Deutschland AG (DE) 2017-10-25 — — EP disclosed
CN-107223121-A Wet stable holographic media 科思创德国股份有限公司 2017-09-29 — — CN disclosed
WO-2016096641-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA COVESTRO DEUTSCHLAND AG (DE) 2016-06-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10329244-B2 Moisture-stable holographic media NEFM, MDM4, BHMT2 PSMB5 2023/4885HSD11B1 3219/4885METAP2 2486/4885
US-20170362165-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA NEFM, MDM4, BHMT2 PSMB5 2023/4885HSD11B1 3219/4885METAP2 2486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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