Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD5 | P21918 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17865171 | 0.87 | ESR2 (0.40) | PTGDR2 | |
| SCHEMBL17844950 | 0.77 | MAOA (0.35) | HTR6HSD11B1DRD2DRD1DRD4 | |
| SCHEMBL17847583 | 0.74 | ERN1 (0.36) | HTR6DRD4 | |
| SCHEMBL29236997 | 0.74 | — | — | |
| SCHEMBL17844924 | 0.74 | DRD2 (0.33) | HTR6HSD11B1DRD2DRD1DRD4 | |
| SCHEMBL21354115 | 0.73 | MTHFD2 (0.39) | DRD4 | |
| SCHEMBL31535207 | 0.71 | MTHFD2 (0.51) | — | |
| SCHEMBL21354142 | 0.71 | MTHFD2 (0.51) | — | |
| SCHEMBL29168627 | 0.71 | ABHD6 (0.42) | DRD2DRD3 | |
| SCHEMBL22466190 | 0.70 | MAPK1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233826-A1 | NEW ANTIBACTERIAL COMPOUNDS | Aziende Chimiche Riunite Angelini Francesco A.C.R. (IT) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016096631-A1 | NEW ANTIBACTERIAL COMPOUNDS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2016-06-23 | — | — | WO | disclosed |