Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 16/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 14/20 | 0.42 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19598957 | 0.85 | GPR119 (0.48) | OPRD1 | |
| SCHEMBL17847963 | 0.82 | OPRD1 (0.61) | OPRD1OPRK1OPRM1KCNH2ABCB11 | |
| SCHEMBL19603373 | 0.79 | OPRD1 (0.38) | OPRD1OPRK1OPRM1KCNH2ABCB11 | |
| SCHEMBL5525678 | 0.76 | OPRD1 (0.71) | OPRD1OPRK1OPRM1KCNH2ABCB11 | |
| SCHEMBL17861660 | 0.76 | OPRD1 (0.47) | OPRD1OPRK1OPRM1KCNH2 | |
| SCHEMBL30351048 | 0.76 | OPRD1 (0.47) | OPRD1OPRK1OPRM1KCNH2 | |
| SCHEMBL19598959 | 0.76 | OPRM1 (0.50) | OPRD1OPRK1OPRM1KCNH2 | |
| SCHEMBL19598955 | 0.75 | OPRD1 (0.43) | OPRD1OPRK1OPRM1KCNH2 | |
| SCHEMBL17861659 | 0.75 | OPRD1 (0.44) | OPRD1OPRK1OPRM1KCNH2 | |
| SCHEMBL19582851 | 0.74 | PARP14 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233825-B1 | DIARYLMETHYLIDENE PIPERIDINE DERIVATIVES AND THEIR USE AS DELTA OPIOID RECEPTOR AGONISTS | PHARMNOVO AB (SE) | 2020-04-29 | — | — | EP | disclosed |
| US-10118921-B2 | Diarylmethylidene piperidine derivatives and their use as delta opoid receptor agnists | PHARMNOVO AB (SE) | 2018-11-06 | — | — | US | disclosed |
| US-20170327491-A1 | DIARYLMETHYLIDENE PIPERIDINE DERIVATIVES AND THEIR USE AS DELTA OPOID RECEPTOR AGNISTS | PHARMNOVO AB (SE) | 2017-11-16 | — | — | US | disclosed |
| EP-3233825-A1 | DIARYLMETHYLIDENE PIPERIDINE DERIVATIVES AND THEIR USE AS DELTA OPIOID RECEPTOR AGONISTS | Pharmnovo AB (SE) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016099393-A1 | DIARYLMETHYLIDENE PIPERIDINE DERIVATIVES AND THEIR USE AS DELTA OPIOID RECEPTOR AGONISTS | PHARMNOVO AB (SE) | 2016-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10118921-B2 | Diarylmethylidene piperidine derivatives and their use as delta opoid receptor agnists | OPRD1, OPRM1, OPRK1 | OPRD1 1/4885OPRK1 3/4885OPRM1 2/4885 |
| US-20170327491-A1 | DIARYLMETHYLIDENE PIPERIDINE DERIVATIVES AND THEIR USE AS DELTA OPOID RECEPTOR AGNISTS | OPRD1, OPRM1, OPRK1 | OPRD1 1/4885OPRK1 3/4885OPRM1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.