Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.64 |
| ▸ | MAOA | P21397 | 9/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | TERT | O14746 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17848261 | 0.85 | MAOB (0.64) | MAOBMAOA | |
| SCHEMBL17848436 | 0.82 | MAOB (0.61) | MAOBMAOA | |
| SCHEMBL17848312 | 0.82 | RAB9A (0.48) | MAOBMAOAALDH1A1NPC1RAB9A | |
| SCHEMBL17848314 | 0.82 | RAB9A (0.48) | MAOBMAOAALDH1A1NPC1RAB9A | |
| SCHEMBL17848310 | 0.80 | MAOB (0.77) | MAOBMAOAALDH1A1 | |
| SCHEMBL754206 | 0.79 | MAOB (0.82) | MAOBMAOA | |
| SCHEMBL560607 | 0.78 | MAOB (0.81) | MAOBMAOA | |
| SCHEMBL7348486 | 0.78 | MAOB (0.83) | MAOBMAOA | |
| SCHEMBL6949626 | 0.75 | MAOB (0.70) | MAOBMAOAALDH1A1RAB9A | |
| SCHEMBL17864854 | 0.74 | MAOB (0.61) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016097345-A1 | LABELLED CHROMONE DERIVATIVES | GE HEALTHCARE LIMITED (GB) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016097345-A1 | LABELLED CHROMONE DERIVATIVES | GE HEALTHCARE LIMITED (GB) | 2016-06-23 | — | — | WO | disclosed |