Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | TERT | O14746 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17848314 | 1.00 | RAB9A (0.48) | RAB9AALDH1A1NPC1MAOAMAOB | |
| SCHEMBL17848427 | 0.87 | MAOB (0.44) | RAB9AALDH1A1MAOAMAOBMAPT | |
| SCHEMBL17848424 | 0.87 | MAOB (0.44) | RAB9AALDH1A1MAOAMAOBMAPT | |
| SCHEMBL17848194 | 0.85 | MAOA (0.42) | RAB9AMAOAMAOBMAPTCYSLTR2 | |
| SCHEMBL17848196 | 0.85 | MAOA (0.42) | RAB9AMAOAMAOBMAPTCYSLTR2 | |
| SCHEMBL17848320 | 0.82 | MAOB (0.64) | RAB9AALDH1A1NPC1MAOAMAOB | |
| SCHEMBL17864853 | 0.79 | MAOA (0.42) | RAB9AALDH1A1MAOAMAOBMAPT | |
| SCHEMBL29076154 | 0.74 | MAPT (0.60) | ALDH1A1NPC1MAOAMAOBMAPT | |
| SCHEMBL28749229 | 0.74 | MAPT (0.60) | ALDH1A1NPC1MAOAMAOBMAPT | |
| SCHEMBL31253971 | 0.71 | ALDH1A1 (0.42) | ALDH1A1MAOBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016097345-A1 | LABELLED CHROMONE DERIVATIVES | GE HEALTHCARE LIMITED (GB) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016097345-A1 | LABELLED CHROMONE DERIVATIVES | GE HEALTHCARE LIMITED (GB) | 2016-06-23 | — | — | WO | disclosed |