Sugi Predict

Sugi Predict / Compounds / SCHEMBL1784863

SCHEMBL1784863

SCHEMBL1784863

[CH2]CN1CC(C)OC(C)C1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ SIGMAR1 Q99720 4/20 0.48
▸ EBP Q15125 2/20 0.48
▸ PDK1 Q15118 1/20 0.41
▸ KDM4E B2RXH2 4/20 0.40
▸ HTT P42858 1/20 0.40
▸ LMNA P02545 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.38
▸ CYP2A13 Q16696 1/20 0.38
▸ ALDH1A1 P00352 2/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ POLB P06746 2/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9449486 1.00 SIGMAR1 (0.48) SIGMAR1EBPPDK1KDM4EHTT
SCHEMBL2552938 0.80 SIGMAR1 (0.55) SIGMAR1EBPPDK1KDM4EHTT
SCHEMBL11962148 0.76 SIGMAR1 (0.56) SIGMAR1EBPPDK1KDM4EHTT
SCHEMBL12125047 0.76 SIGMAR1 (0.56) SIGMAR1EBPPDK1KDM4EHTT
SCHEMBL12125120 0.76 SIGMAR1 (0.56) SIGMAR1EBPPDK1KDM4EHTT
SCHEMBL4550370 0.76 SIGMAR1 (0.56) SIGMAR1EBPPDK1KDM4EHTT
SCHEMBL14782687 0.75 — —
SCHEMBL17012154 0.74 SIGMAR1 (0.48) SIGMAR1EBPPDK1KDM4EHTT
SCHEMBL13177783 0.74 SIGMAR1 (0.48) SIGMAR1EBPPDK1KDM4EHTT
SCHEMBL14067375 0.74 SIGMAR1 (0.48) SIGMAR1EBPPDK1KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230132298-A1 OXABOROLE ESTERS AND USES THEREOF ANACOR PHARMACEUTICALS, LLC 2023-04-27 — — US claimed
US-11578087-B2 Oxaborole esters and uses thereof ANACOR PHARMACEUTICALS, INC. (US) 2023-02-14 — — US claimed
US-20210101916-A1 OXABOROLE ESTERS AND USES THEREOF ANACOR PHARMACEUTICALS, INC. 2021-04-08 — — US claimed
US-20130210769-A1 COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY IRM LLC (BM) 2013-08-15 — — US claimed
US-8431607-B2 Compounds and compositions as inhibitors of cannabinoid receptor 1 activity IRM LLC, A DELAWARE LIMITED LIABILITY COMPANY (BM) 2013-04-30 — — US claimed
US-20100234365-A1 COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY IRM LLC (BM) 2010-09-16 — — US claimed
EP-2121598-A2 COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY IRM LLC (BM) 2009-11-25 — — EP claimed
WO-2008076754-A2 COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY IRM LLC (BM) 2008-06-26 — — WO claimed
EP-0668302-B1 Catalyst for reactive hot melt adhesives NAT STARCH CHEM INVEST (US) 1999-12-22 — — EP claimed
US-20230132298-A1 OXABOROLE ESTERS AND USES THEREOF ANACOR PHARMACEUTICALS, LLC 2023-04-27 — — US disclosed
US-11578087-B2 Oxaborole esters and uses thereof ANACOR PHARMACEUTICALS, INC. (US) 2023-02-14 — — US disclosed
EP-3578562-B1 L-VALINATE AMIDE BENZOXABOROLE DERIVATIVES FOR THE TREATMENT OF PARASITIC DISEASES ANACOR PHARMACEUTICALS INC (US) 2021-06-23 — — EP disclosed
US-20210101916-A1 OXABOROLE ESTERS AND USES THEREOF ANACOR PHARMACEUTICALS, INC. 2021-04-08 — — US disclosed
US-10882872-B2 Oxaborole esters and uses thereof ANACOR PHARMACEUTICALS, INC. (US) 2021-01-05 — — US disclosed
US-5364844-A Hypotensive agents SANKYO COMPANY, LIMITED (JP) 1994-11-15 — — US disclosed
EP-0326364-B1 Renin inhibitory oligopeptides, their preparation and use SANKYO CO (JP) 1994-06-22 — — EP disclosed
US-5199970-A Preemergence; postemergence; monocotyledonous weeds; moderately toxic ALKALOIDA VEGYESZETI GYAR (HU) 1993-04-06 — — US disclosed
EP-0426491-A2 Herbicidal, optically active or racemic substituted propionic acid derivatives, herbicide compositions containing them and process for preparing same ALKALOIDA VEGYESZETI GYAR (HU) 1991-05-08 — — EP disclosed
EP-0326364-A2 Renin inhibitory oligopeptides, their preparation and use Sankyo Company Limited (JP) 1989-08-02 — — EP disclosed
EP-0274259-A2 New renin-inhibitory oligopeptides, their preparaton and their use Sankyo Company Limited (JP) 1988-07-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230132298-A1 OXABOROLE ESTERS AND USES THEREOF OXA1L, HSD17B12, OXER1 SIGMAR1 1855/4885EBP 404/4885PDK1 1923/4885
US-10882872-B2 Oxaborole esters and uses thereof OXA1L, HSD17B12, OXER1 SIGMAR1 1855/4885EBP 404/4885PDK1 1923/4885
US-20210101916-A1 OXABOROLE ESTERS AND USES THEREOF OXA1L, HSD17B12, OXER1 SIGMAR1 1855/4885EBP 404/4885PDK1 1923/4885
US-11578087-B2 Oxaborole esters and uses thereof OXA1L, HSD17B12, OXER1 SIGMAR1 1855/4885EBP 404/4885PDK1 1923/4885
US-20130210769-A1 COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY CNR1, CNR2, FAAH SIGMAR1 408/4885EBP 822/4885PDK1 3859/4885
US-20100234365-A1 COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY CNR1, CNR2, FAAH SIGMAR1 408/4885EBP 822/4885PDK1 3859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.