Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 9/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17849020 | 0.81 | KMT2A (0.38) | KMT2ACA12CA1CA2CA7 | |
| SCHEMBL17848980 | 0.80 | ALDH1A1 (0.35) | GAAALDH1A1 | |
| SCHEMBL17849026 | 0.78 | MAPT (0.36) | KMT2ACA12CA1CA2CA7 | |
| Methyl Alcohol SCHEMBL17848974 | 0.72 | MEN1 (0.35) | KMT2AL3MBTL1KDM4EGAAPKM | |
| SCHEMBL1170580 | 0.70 | CTSL (0.49) | KMT2ACA12CA1L3MBTL1HTT | |
| SCHEMBL10334067 | 0.70 | KMT2A (0.71) | KMT2AEGFRCA12CA1CA2 | |
| SCHEMBL11202032 | 0.69 | KMT2A (0.66) | KMT2AEGFRCA12CA1CA2 | |
| SCHEMBL1977674 | 0.67 | KMT2A (0.71) | KMT2AEGFRCA12CA1CA2 | |
| SCHEMBL14400343 | 0.66 | EGFR (0.62) | KMT2AEGFRCA12CA1CA2 | |
| SCHEMBL17848982 | 0.65 | CA12 (0.43) | KMT2AEGFRCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233886-B1 | COMPOUNDS IN THE FAMILY OF N-ACYLAMINO-AMIDES, COMPOSITIONS COMPRISING THEM, AND USES | OREAL (FR) | 2020-02-26 | — | — | EP | disclosed |
| US-20170360667-A1 | NEW COMPOUNDS IN THE FAMILY OF N-ACYLAMINO-AMIDES, COMPOSITIONS COMPRISING THEM, AND USES | L'OREAL (FR) | 2017-12-21 | — | — | US | disclosed |
| EP-3233886-A1 | COMPOUNDS IN THE FAMILY OF N-ACYLAMINO-AMIDES, COMPOSITIONS COMPRISING THEM, AND USES | L'Oréal (FR) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016096804-A1 | COMPOUNDS IN THE FAMILY OF N-ACYLAMINO-AMIDES, COMPOSITIONS COMPRISING THEM, AND USES | L'OREAL (FR) | 2016-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170360667-A1 | NEW COMPOUNDS IN THE FAMILY OF N-ACYLAMINO-AMIDES, COMPOSITIONS COMPRISING THEM, AND USES | H1-0, CRY1, CCNA1 | KMT2A 1630/4885EGFR 993/4885CA12 1696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.