SCHEMBL17849026

SCHEMBL17849026

CC(=O)N(CC(=O)O)C(=O)C(Nc1ccc(O)cc1)C(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.36
CYP1A1 P04798 2/20 0.36
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
MEN1 O00255 1/20 0.36
BRD4 O60885 1/20 0.36
NR1I2 O75469 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MB P02144 1/20 0.36
CA3 P07451 1/20 0.36
CYP3A4 P08684 1/20 0.36
RARG P13631 1/20 0.36
TSHR P16473 1/20 0.36
ALOX5AP P20292 1/20 0.36
CA4 P22748 1/20 0.36
CA7 P43166 1/20 0.36
KMT2A Q03164 1/20 0.36
NR1I3 Q14994 1/20 0.36
CA9 Q16790 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17848962 0.85 ALDH1A1 (0.41) MAPTMEN1ALDH1A1CYP3A4TSHR
SCHEMBL17849020 0.83 KMT2A (0.38) CA12CA1CA2MEN1ALDH1A1
SCHEMBL17848980 0.82 ALDH1A1 (0.35) MAPTALDH1A1GAANPC1
SCHEMBL17848983 0.81 MEN1 (0.35) MAPTMEN1ALDH1A1KMT2AGAA
Methyl Alcohol SCHEMBL17848974 0.80 MEN1 (0.35) MAPTMEN1ALDH1A1KMT2AGAA
SCHEMBL17848988 0.78 KMT2A (0.46) CA12CA1CA2ALDH1A1CA7
SCHEMBL1170580 0.76 CTSL (0.49) MAPTCA12CA1MEN1ALDH1A1
SCHEMBL11196490 0.74 ADAMTS4 (0.51) MAPTCYP1A1CA12CA1CA2
SCHEMBL11196494 0.74 ADAMTS4 (0.51) MAPTCYP1A1CA12CA1CA2
SCHEMBL9724064 0.70 SLC7A5 (0.57) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3233886-B1 COMPOUNDS IN THE FAMILY OF N-ACYLAMINO-AMIDES, COMPOSITIONS COMPRISING THEM, AND USES OREAL (FR) 2020-02-26 EP disclosed
US-20170360667-A1 NEW COMPOUNDS IN THE FAMILY OF N-ACYLAMINO-AMIDES, COMPOSITIONS COMPRISING THEM, AND USES L'OREAL (FR) 2017-12-21 US disclosed
EP-3233886-A1 COMPOUNDS IN THE FAMILY OF N-ACYLAMINO-AMIDES, COMPOSITIONS COMPRISING THEM, AND USES L'Oréal (FR) 2017-10-25 EP disclosed
WO-2016096804-A1 COMPOUNDS IN THE FAMILY OF N-ACYLAMINO-AMIDES, COMPOSITIONS COMPRISING THEM, AND USES L'OREAL (FR) 2016-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170360667-A1 NEW COMPOUNDS IN THE FAMILY OF N-ACYLAMINO-AMIDES, COMPOSITIONS COMPRISING THEM, AND USES H1-0, CRY1, CCNA1 MAPT 3886/4885CYP1A1 844/4885CA12 1696/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.