Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 4/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17849030 | 0.99 | NCF1 (0.38) | NCF1EGFRJAK2JAK1JAK3 | |
| SCHEMBL16078200 | 0.86 | EGFR (0.40) | EGFRTSHRKDM4ELMNASMN1; SMN2 | |
| SCHEMBL1840926 | 0.86 | EGFR (0.42) | EGFRTSHRKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1841281 | 0.84 | EGFR (0.41) | EGFRTSHRKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3318724 | 0.84 | EGFR (0.41) | EGFRTSHRKDM4EMEN1KMT2A | |
| SCHEMBL19688877 | 0.81 | EGFR (0.37) | EGFRJAK2JAK1JAK3TSHR | |
| SCHEMBL1231181 | 0.80 | EGFR (0.40) | EGFRJAK2JAK1JAK3MEN1 | |
| Hydrochloric Acid SCHEMBL17849041 | 0.80 | EGFR (0.36) | EGFRTSHRMEN1KMT2ADRD2 | |
| SCHEMBL1840855 | 0.80 | KAT2B (0.45) | EGFRJAK2JAK1JAK3KDM4E | |
| SCHEMBL9970803 | 0.80 | HTR1B (0.41) | EGFRKDM4EHRH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10240043-B2 | Use for dyeing keratin fibres of a compound of azomethine type bearing two pyrazolopyridine units | L'OREAL (FR) | 2019-03-26 | — | — | US | disclosed |
| EP-3233855-B1 | USE FOR DYEING KERATIN FIBRES OF A COMPOUND OF AZOMETHINE TYPE BEARING TWO PYRAZOLOPYRIDINE UNITS | OREAL (FR) | 2018-10-31 | — | — | EP | disclosed |
| US-20170349753-A1 | USE FOR DYEING KERATIN FIBRES OF A COMPOUND OF AZOMETHINE TYPE BEARING TWO PYRAZOLOPYRIDINE UNITS | L'OREAL (FR) | 2017-12-07 | — | — | US | disclosed |
| EP-3233855-A1 | USE FOR DYEING KERATIN FIBRES OF A COMPOUND OF AZOMETHINE TYPE BEARING TWO PYRAZOLOPYRIDINE UNITS | L'OREAL (FR) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016097198-A1 | USE FOR DYEING KERATIN FIBRES OF A COMPOUND OF AZOMETHINE TYPE BEARING TWO PYRAZOLOPYRIDINE UNITS | L'OREAL (FR) | 2016-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349753-A1 | USE FOR DYEING KERATIN FIBRES OF A COMPOUND OF AZOMETHINE TYPE BEARING TWO PYRAZOLOPYRIDINE UNITS | KRT18, DSP, TMPO | NCF1 610/4885EGFR 2577/4885JAK2 3213/4885 |
| US-10240043-B2 | Use for dyeing keratin fibres of a compound of azomethine type bearing two pyrazolopyridine units | KRT18, DSP, TMPO | NCF1 610/4885EGFR 2577/4885JAK2 3213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.