SCHEMBL17849093

SCHEMBL17849093

O=C1C=CC(=O)c2cc3cc(Br)ccc3cc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.48
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
ALDH1A1 P00352 1/20 0.45
MAPT P10636 1/20 0.45
KMT2A Q03164 1/20 0.45
S100A4 P26447 1/20 0.41
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
MAOB P27338 2/20 0.37
CDC25B P30305 2/20 0.37
IDO1 P14902 1/20 0.37
MAOA P21397 1/20 0.37
AKT1 P31749 1/20 0.37
SNCA P37840 1/20 0.37
MAP2K1 Q02750 1/20 0.37
PIN1 Q13526 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29681689 1.00 CYP2A6 (0.48) CYP2A6KDM4EMEN1ALDH1A1MAPT
SCHEMBL22361364 0.89 CYP2A6 (0.39) CYP2A6KDM4EMEN1ALDH1A1MAPT
SCHEMBL15210982 0.82 S100A4 (0.56) CYP2A6KDM4EMEN1ALDH1A1MAPT
SCHEMBL29649816 0.82 S100A4 (0.56) CYP2A6KDM4EMEN1ALDH1A1MAPT
SCHEMBL15210826 0.82 S100A4 (0.56) CYP2A6KDM4EMEN1ALDH1A1MAPT
SCHEMBL31036879 0.81 PTPRC (0.43) CYP2A6KDM4EMEN1ALDH1A1MAPT
SCHEMBL11052384 0.79 S100A4 (0.58) S100A4CA1CA2CA4CA7
SCHEMBL16407237 0.77 CYP2A6 (0.64) CYP2A6KDM4EMEN1ALDH1A1MAPT
SCHEMBL23312077 0.75 CYP2A6 (0.68) CYP2A6KDM4EMEN1ALDH1A1MAPT
SCHEMBL17849092 0.75 CYP2A6 (0.68) CYP2A6KDM4EMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114560885-B Sound-sensitive agent with low phototoxicity and preparation method and application thereof 北京理工大学 2023-03-14 CN disclosed
CN-114560885-A Sound-sensitive agent with low phototoxicity and preparation method and application thereof 北京理工大学 2022-05-31 CN disclosed
US-10752730-B2 Quantitative intramolecular fission in oligoacenes, materials, and methods of use thereof THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2020-08-25 US disclosed
US-10752730-B2 Quantitative intramolecular fission in oligoacenes, materials, and methods of use thereof THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2020-08-25 US disclosed
US-20180258217-A1 QUANTITATIVE INTRAMOLECULAR FISSION IN OLIGOACENES, MATERIALS, AND METHODS OF USE THEREOF UNITED STATES DEPARTMENT OF ENERGY 2018-09-13 US disclosed
WO-2016100754-A1 QUANTITATIVE INTRAMOLECULAR FISSION IN OLIGOACENES, MATERIALS, AND METHODS OF USE THEREOF THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2016-06-23 WO disclosed
WO-2016100754-A1 QUANTITATIVE INTRAMOLECULAR FISSION IN OLIGOACENES, MATERIALS, AND METHODS OF USE THEREOF THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2016-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10752730-B2 Quantitative intramolecular fission in oligoacenes, materials, and methods of use thereof SPIN1, SPIN3, ESPL1 CYP2A6 4774/4885KDM4E 4485/4885MEN1 2754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.