Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | UQCRB | P14927 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | RORA | P35398 | 1/20 | 0.57 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | IKBKB | O14920 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20657540 | 0.84 | FFAR4 (0.72) | FFAR1FFAR4ALDH1A1MEN1KMT2A | |
| SCHEMBL10013443 | 0.84 | PTPN5 (0.68) | FFAR1FFAR4ALDH1A1MEN1KMT2A | |
| SCHEMBL17849569 | 0.83 | MAPT (0.58) | FFAR1FFAR4ALDH1A1MEN1KMT2A | |
| SCHEMBL208685 | 0.83 | UQCRB (0.67) | ALDH1A1MEN1KMT2AUQCRBCA1 | |
| SCHEMBL5800778 | 0.82 | FFAR4 (0.68) | FFAR4ALDH1A1MEN1KMT2APKM | |
| SCHEMBL812679 | 0.81 | ALDH1A1 (0.83) | FFAR1FFAR4ALDH1A1MEN1KMT2A | |
| SCHEMBL27811906 | 0.80 | ALDH1A1 (0.71) | FFAR1FFAR4ALDH1A1MEN1KMT2A | |
| SCHEMBL13433558 | 0.79 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2AUQCRBCA1 | |
| SCHEMBL1040954 | 0.79 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2AUQCRBCA1 | |
| SCHEMBL13615206 | 0.78 | FFAR4 (0.60) | FFAR1FFAR4ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371286-B2 | Pharmaceutical composition with enhanced efficacy for inhibiting angiogenesis | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2016-06-21 | — | — | US | disclosed |