Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.77 |
| ▸ | RAD52 | P43351 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | PKLR | P30613 | 1/20 | 0.57 |
| ▸ | CYTH2 | Q99418 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.52 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10013445 | 0.83 | MEN1 (0.60) | MEN1KMT2APKMPKLRALDH1A1 | |
| SCHEMBL10013441 | 0.83 | MEN1 (0.60) | MEN1KMT2APKMPKLRALDH1A1 | |
| SCHEMBL17849568 | 0.82 | CYTH2 (0.61) | MEN1KMT2ACYTH2MAPTALDH1A1 | |
| SCHEMBL7178299 | 0.81 | CYTH2 (0.73) | MEN1KMT2ACYTH2MAPTALDH1A1 | |
| SCHEMBL28326534 | 0.81 | HSD17B2 (0.61) | MEN1KMT2APKMPKLRMAPT | |
| SCHEMBL16187949 | 0.81 | KMT2A (0.60) | MEN1KMT2AMAPTALDH1A1HSD11B1 | |
| SCHEMBL12878224 | 0.80 | MEN1 (0.74) | MEN1KMT2APKMMAPTALDH1A1 | |
| SCHEMBL10987158 | 0.79 | PKM (0.61) | MEN1KMT2APKMPKLRALDH1A1 | |
| SCHEMBL808105 | 0.78 | ATM (0.72) | MEN1KMT2APKMPKLRMAPT | |
| SCHEMBL3260752 | 0.78 | MEN1 (0.62) | MEN1KMT2APKMMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371286-B2 | Pharmaceutical composition with enhanced efficacy for inhibiting angiogenesis | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2016-06-21 | — | — | US | disclosed |