Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UQCRB | P14927 | 2/20 | 0.72 |
| ▸ | CA1 | P00915 | 2/20 | 0.70 |
| ▸ | CA2 | P00918 | 2/20 | 0.70 |
| ▸ | IKBKB | O14920 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
| ▸ | CDK1 | P06493 | 1/20 | 0.59 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.59 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.59 |
| ▸ | CDK2 | P24941 | 1/20 | 0.59 |
| ▸ | CDK7 | P50613 | 1/20 | 0.59 |
| ▸ | CCNH | P51946 | 1/20 | 0.59 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15604702 | 0.87 | FFAR1 (0.74) | UQCRBCA1CA2ALDH1A1SMN1; SMN2 | |
| SCHEMBL3701951 | 0.85 | CA12 (0.71) | CA1CA2ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL15603531 | 0.85 | FFAR4 (0.76) | UQCRBCA1CA2IKBKBALDH1A1 | |
| SCHEMBL7176442 | 0.84 | UQCRB (1.00) | UQCRBCA1CA2IKBKBALDH1A1 | |
| SCHEMBL23057261 | 0.83 | IDO1 (0.72) | CA1CA2ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL6842347 | 0.82 | FFAR1 (0.77) | UQCRBCA1CA2IKBKBALDH1A1 | |
| SCHEMBL259382 | 0.82 | CA12 (0.66) | CA1CA2ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL31681311 | 0.82 | CA12 (0.66) | CA1CA2ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL12042475 | 0.82 | ALDH1A1 (0.71) | UQCRBCA1CA2IKBKBALDH1A1 | |
| SCHEMBL1592806 | 0.81 | LMNA (0.60) | UQCRBCA1CA2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371286-B2 | Pharmaceutical composition with enhanced efficacy for inhibiting angiogenesis | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2016-06-21 | — | — | US | disclosed |