SCHEMBL6842347

SCHEMBL6842347

CC(C)(C)c1ccc(S(=O)(=O)Nc2cccc(C(F)(F)F)c2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.77
FFAR4 Q5NUL3 2/20 0.77
CDK1 P06493 2/20 0.77
CCNB1 P14635 2/20 0.77
CCNA2 P20248 2/20 0.77
CDK2 P24941 2/20 0.77
CDK7 P50613 2/20 0.77
CCNH P51946 2/20 0.77
CCNA1 P78396 2/20 0.77
UQCRB P14927 1/20 0.68
CA1 P00915 1/20 0.67
CA2 P00918 1/20 0.67
IKBKB O14920 1/20 0.64
MAPT P10636 5/20 0.63
CYP1A2 P05177 1/20 0.63
CYP3A4 P08684 1/20 0.63
MAPK1 P28482 1/20 0.63
CYP2C19 P33261 1/20 0.63
BRD4 O60885 1/20 0.61
KMT2A Q03164 4/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15603554 0.94 FFAR1 (0.72) FFAR1FFAR4CDK1CCNB1CCNA2
SCHEMBL30230090 0.87 FFAR1 (0.63) FFAR1FFAR4CDK1CCNB1CCNA2
SCHEMBL121452 0.85 CDK1 (0.76) FFAR1FFAR4CDK1CCNB1CCNA2
SCHEMBL5894008 0.84 CDK1 (0.74) FFAR1FFAR4CDK1CCNB1CCNA2
SCHEMBL22516007 0.84 CDK1 (0.74) FFAR1FFAR4CDK1CCNB1CCNA2
SCHEMBL6844057 0.83 CDK1 (0.65) FFAR1FFAR4CDK1CCNB1CCNA2
SCHEMBL15603531 0.82 FFAR4 (0.76) FFAR1FFAR4CDK1CCNB1CCNA2
SCHEMBL17849567 0.82 UQCRB (0.72) FFAR1FFAR4CDK1CCNB1CCNA2
SCHEMBL678551 0.82 CA1 (0.65) FFAR1FFAR4CDK1CCNB1CCNA2
SCHEMBL23447674 0.82 MAPT (0.63) FFAR1FFAR4CDK1CCNB1CCNA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040220268-A1 Compound that directly stimulates phospholipase C activity POSTECH FOUNDATION (KR) 2004-11-04 US claimed
US-20040220268-A1 Compound that directly stimulates phospholipase C activity POSTECH FOUNDATION (KR) 2004-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040220268-A1 Compound that directly stimulates phospholipase C activity PLD1, PLA2G4C, PLD2 FFAR1 1147/4885FFAR4 1822/4885CDK1 854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.