SCHEMBL439769

SCHEMBL439769

c1ccc(-c2ccc[nH]2)nc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.54
LMNA P02545 4/20 0.54
CCR1 P32246 2/20 0.54
CCR5 P51681 2/20 0.54
CCR8 P51685 2/20 0.54
CYP1A2 P05177 1/20 0.54
POLB P06746 1/20 0.54
METAP1 P53582 1/20 0.54
BLM P54132 1/20 0.54
HIF1A Q16665 1/20 0.54
DOHH Q9BU89 1/20 0.54
P4HTM Q9NXG6 1/20 0.54
KDM4C Q9H3R0 1/20 0.50
NPC1 O15118 6/20 0.47
RAB9A P51151 6/20 0.47
SMN1; SMN2 Q16637 4/20 0.46
TP53 P04637 3/20 0.46
TDP1 Q9NUW8 3/20 0.46
ALOX15 P16050 3/20 0.46
L3MBTL1 Q9Y468 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29529148 1.00 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8
SCHEMBL27768754 0.98 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8
Pyridine SCHEMBL28181012 0.92 KDM4C (0.49) KDM4ELMNACCR1CCR5CCR8
SCHEMBL28027112 0.88 FKBP5 (0.53) KDM4ELMNACCR1CCR5CCR8
SCHEMBL18204056 0.87 KDM4E (0.64) KDM4ELMNACCR1CCR5CCR8
SCHEMBL17850816 0.86
Quinoline SCHEMBL28115235 0.86 ALDH1A1 (0.55) KDM4ELMNACCR1CCR5CCR8
SCHEMBL28361630 0.85 NPC1 (0.48) KDM4ELMNACCR1CCR5CCR8
SCHEMBL21578438 0.84 KDM4E (0.46) KDM4ELMNACCR1CCR5CCR8
SCHEMBL2487118 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 700 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113946096-B Photoresist for semiconductor fabrication 台湾积体电路制造股份有限公司 2024-08-02 CN claimed
US-20240124770-A1 COMPOUND, GUEST MATERIAL OF LIGHT-EMITTING LAYER, ORGANIC ELECTROLUMINESCENT DEVICE, AND DISPLAY DEVICE BEIJING NORMAL UNIVERSITY (CN) 2024-04-18 US claimed
CN-116034301-A System and method for simultaneous near infrared and visible imaging 光明之火生物科学公司 2023-04-28 CN claimed
WO-2022166889-A1 COMPOUND, GUEST MATERIAL OF LIGHT-EMITTING LAYER, ORGANIC ELECTROLUMINESCENT DEVICE, AND DISPLAY DEVICE 北京师范大学 2022-08-11 WO claimed
CN-113946096-A Photoresist for semiconductor fabrication 台湾积体电路制造股份有限公司 2022-01-18 CN claimed
CN-112979713-A Compound, light-emitting layer guest material, organic electroluminescent device and display device 北京师范大学 2021-06-18 CN claimed
EP-2499181-B1 POLYMER FOR OPTOELECTRONIC DEVICE BOE TECHNOLOGY GROUP CO LTD (CN) 2020-05-13 EP claimed
CN-107698558-B A kind of preparation method and its purification method of azepine episulfide 温州大学 2019-04-02 CN claimed
CN-107698558-A The preparation method and its purification method of a kind of azepine episulfide 温州大学 2018-02-16 CN claimed
CN-107382964-A The method for preparing Pyridylpyrrole and its derivative 华北理工大学 2017-11-24 CN claimed
CN-1633445-A Process for preparing eplerenone PHARMACIA CORP (US) 2005-06-29 CN claimed
US-6902830-B2 Organometallic complexes as phosphorescent emitters in organic LEDs THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2005-06-07 US claimed
US-20040262576-A1 Organometallic complexes as phosphorescent emitters in organic LEDs THOMPSON MARK E (US) 2004-12-30 US claimed
US-20040072018-A1 Metallic complexes covalently bound to conjugated polymers and electronic devices containing such compositions LG CHEM, LTD. (KR) 2004-04-15 US claimed
WO-2004015025-A1 METALLIC COMPLEXES COVALENTLY BOUND TO CONJUGATED POLYMERS AND ELECTRONIC DEVICES CONTAINING SUCH COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2004-02-19 WO claimed
US-6392047-B1 COUPLING OF THE CORRESPONDING AROMATIC COMPOUND WITH AN AROMATIC BORON COMPOUND CLARIANT GMBH (DE) 2002-05-21 US claimed
EP-1200373-A1 METHOD FOR PRODUCING BIARYLS USING PALLADAPHOSPHACYCLOBUTANE CATALYSIS Clariant GmbH (DE) 2002-05-02 EP claimed
WO-2001004076-A1 METHOD FOR PRODUCING BIARYLS USING PALLADAPHOSPHACYCLOBUTANE CATALYSIS CLARIANT GMBH (DE) 2001-01-18 WO claimed
WO-1995000506-A1 SUBSTITUTED PYRIDYLPYRROLES AND THEIR USE FOR CONTROLLING ANIMAL PESTS BAYER AKTIENGESELLSCHAFT (DE) 1995-01-05 WO claimed
US-4666249-A Surface-treated contact lens and method of producing SOLA U.S.A. INC. (US) 1987-05-19 US claimed