Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 5/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17733514 | 1.00 | ALK (0.34) | ALKPLA2G2APLA2G4AHSP90AA1HSP90AB1 | |
| SCHEMBL17733351 | 1.00 | ALK (0.34) | ALKPLA2G2APLA2G4AHSP90AA1HSP90AB1 | |
| SCHEMBL17733377 | 0.97 | PLA2G2A (0.36) | ALKPLA2G2APLA2G4AHSP90AA1HSP90AB1 | |
| SCHEMBL17853225 | 0.97 | PLA2G2A (0.36) | ALKPLA2G2APLA2G4AHSP90AA1HSP90AB1 | |
| SCHEMBL17733493 | 0.97 | PLA2G2A (0.36) | ALKPLA2G2APLA2G4AHSP90AA1HSP90AB1 | |
| SCHEMBL17733223 | 0.95 | PLA2G2A (0.34) | ALKPLA2G2APLA2G4AHSP90AA1HSP90AB1 | |
| SCHEMBL17853232 | 0.95 | PLA2G2A (0.34) | ALKPLA2G2APLA2G4AHSP90AA1HSP90AB1 | |
| SCHEMBL17853200 | 0.95 | PLA2G2A (0.34) | ALKPLA2G2APLA2G4AHSP90AA1HSP90AB1 | |
| SCHEMBL17853233 | 0.94 | PGR (0.33) | ALKPLA2G2APLA2G4AHSP90AA1HSP90AB1 | |
| SCHEMBL18212059 | 0.94 | PLA2G2A (0.35) | ALKPLA2G2APLA2G4AHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160181526-A1 | AROMATIC AMINE COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2016-06-23 | — | — | US | disclosed |
| US-20160181526-A1 | AROMATIC AMINE COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2016-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160181526-A1 | AROMATIC AMINE COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE | AOC2, PNMT, TYR | ALK 76/4885PLA2G2A 4251/4885PLA2G4A 4697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.