Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19656582 | 0.84 | GSK3B (0.45) | MAPTALDH1A1KDM1ASMN1; SMN2GAA | |
| SCHEMBL14823736 | 0.80 | MAPK14 (0.56) | MAPTALDH1A1KDM1ACA1CA2 | |
| SCHEMBL15999132 | 0.80 | MAP4K4 (0.52) | PDE3BPDE3ASLC22A12MAP4K4RARB | |
| SCHEMBL10269902 | 0.79 | PTGS1 (0.55) | MAPTSMN1; SMN2SLC6A9RARBNPC1 | |
| SCHEMBL15605814 | 0.78 | GAPDH (0.44) | MAPTALDH1A1KDM1ASMN1; SMN2GAA | |
| SCHEMBL16844139 | 0.78 | PDE3B (0.42) | KDM1APDE3BPDE3ASLC22A12 | |
| SCHEMBL10058042 | 0.78 | MAPT (0.66) | MAPTALDH1A1SMN1; SMN2CA1CA2 | |
| SCHEMBL2559215 | 0.78 | RARB (0.59) | MAPTALDH1A1SMN1; SMN2CA1CA2 | |
| SCHEMBL5142555 | 0.77 | CYP2C19 (0.58) | SMN1; SMN2CA1CA2MAP4K4NPC1 | |
| SCHEMBL397141 | 0.77 | KIF11 (0.61) | PDE3BPDE3ACYP11B1CYP11B2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016096081-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2016-06-23 | — | — | WO | disclosed |