Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 7/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17855536 | 0.84 | MAPT (0.48) | KDM1APDE3BPDE3AP4HBGAA | |
| SCHEMBL17857765 | 0.79 | GSK3B (0.63) | GSK3BCA1CA2ALDH1A1MAPT | |
| SCHEMBL15999132 | 0.79 | MAP4K4 (0.52) | PDE3BPDE3ASLC22A12MAP4K4RARB | |
| SCHEMBL14240796 | 0.77 | RAB9A (0.49) | GSK3BKDM1AP4HBGAASMN1; SMN2 | |
| SCHEMBL11983785 | 0.77 | GSK3B (0.70) | GSK3BSMN1; SMN2CA1CA2ALDH1A1 | |
| SCHEMBL7442833 | 0.77 | MMP2 (0.41) | RORCKDM1APDE3BPDE3AP4HB | |
| SCHEMBL7442828 | 0.77 | MMP2 (0.41) | RORCKDM1APDE3BPDE3AP4HB | |
| SCHEMBL16841030 | 0.76 | RORC (0.43) | RORCKDM1APDE3BPDE3ASLC22A12 | |
| SCHEMBL15613720 | 0.76 | KDM4E (0.43) | RORCKDM1APDE3BPDE3AGAA | |
| SCHEMBL19367865 | 0.76 | GSK3B (0.59) | GSK3BSMN1; SMN2CA1CA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170342324-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342324-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MTX1, S100A11, MCRS1 | GSK3B 746/4885RORC 1610/4885KDM1A 3523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.